Trial Outcomes & Findings for Evaluation of an Intervention for Adolescent Girls in Karnataka (NCT NCT01996241)

NCT ID: NCT01996241

Last Updated: 2019-10-15

Results Overview

This outcome will be assessed using data collected from all study participants at end-line, using the face-to-face questionnaire.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

2457 participants

Primary outcome timeframe

May-August 2016 (cohort one) and May-August 2017 (cohort two)

Results posted on

2019-10-15

Participant Flow

80 of 121 village clusters in Vijayapura and Bagalkote districts, Karnataka State, were randomly selected (40 intervention; 40 control). Girls were recruited from two successive academic years (cohorts 1 and 2) to increase study power and achieve required sample size. Analysis was planned by trial arm rather than separately for two study cohorts.

Unit of analysis: Village cluster

Participant milestones

Participant milestones
Measure
Intervention Village Cluster
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
Control Village Cluster
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Overall Study
STARTED
1164 40
1111 40
Overall Study
COMPLETED
912 40
876 40
Overall Study
NOT COMPLETED
252 0
235 0

Reasons for withdrawal

Reasons for withdrawal
Measure
Intervention Village Cluster
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
Control Village Cluster
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Overall Study
Lost to Follow-up
252
235

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention Village Cluster
n=1164 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
Control Village Cluster
n=1111 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Total
n=2275 Participants
Total of all reporting groups
Age, Continuous
13.0 years
n=1164 Participants
13.0 years
n=1111 Participants
13.0 years
n=2275 Participants
Sex: Female, Male
Female
1164 Participants
n=1164 Participants
1111 Participants
n=1111 Participants
2275 Participants
n=2275 Participants
Sex: Female, Male
Male
0 Participants
n=1164 Participants
0 Participants
n=1111 Participants
0 Participants
n=2275 Participants
Race and Ethnicity Not Collected
0 Participants
Race and Ethnicity were not collected from any participant.
Region of Enrollment
India
1164 participants
n=1164 Participants
1111 participants
n=1111 Participants
2275 participants
n=2275 Participants
District
Bagalkote
639 Participants
n=1164 Participants
620 Participants
n=1111 Participants
1259 Participants
n=2275 Participants
District
Vijapura
525 Participants
n=1164 Participants
491 Participants
n=1111 Participants
1016 Participants
n=2275 Participants
Caste (ST vs. SC)
Scheduled Tribe
278 Participants
n=1164 Participants
209 Participants
n=1111 Participants
487 Participants
n=2275 Participants
Caste (ST vs. SC)
Schedued Caste
886 Participants
n=1164 Participants
902 Participants
n=1111 Participants
1788 Participants
n=2275 Participants
Non-literate Household Head
748 Participants
n=1164 Participants
667 Participants
n=1111 Participants
1415 Participants
n=2275 Participants
Village Type (Feeder vs. Main)
Feeder Village
321 Participants
n=1164 Participants
346 Participants
n=1111 Participants
667 Participants
n=2275 Participants
Village Type (Feeder vs. Main)
Main Village
843 Participants
n=1164 Participants
765 Participants
n=1111 Participants
1608 Participants
n=2275 Participants
Household wealth quintile (Poorest)
228 Participants
n=1164 Participants
227 Participants
n=1111 Participants
455 Participants
n=2275 Participants
Devadasi Family
65 Participants
n=1164 Participants
47 Participants
n=1111 Participants
112 Participants
n=2275 Participants

PRIMARY outcome

Timeframe: May-August 2016 (cohort one) and May-August 2017 (cohort two)

This outcome will be assessed using data collected from all study participants at end-line, using the face-to-face questionnaire.

Outcome measures

Outcome measures
Measure
SC/ST Girls in Intervention Village Cluster
n=912 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
SC/ST Girls in Control Village Cluster
n=876 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Number of Participants Completing Secondary School [Sit 10th Standard Exam]
680 Participants
658 Participants

PRIMARY outcome

Timeframe: May-August 2016 (cohort one) and May-August 2017 (cohort two)

This outcome will be assessed using data collected from all study participants at end-line, using the face-to-face questionnaire.

Outcome measures

Outcome measures
Measure
SC/ST Girls in Intervention Village Cluster
n=912 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
SC/ST Girls in Control Village Cluster
n=876 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Number of Participants Married [by Trial End Line]
92 Participants
84 Participants

SECONDARY outcome

Timeframe: March-May 2014

Population: outcome assessed using data from cohort two girls only, using the baseline face-to-face questionnaire.

Due to delays at the start of the cluster-Randomized Controlled Trial, the intervention had not started when cohort one girls were interviewed. This outcome will be assessed using data from cohort two girls only, using the face-to-face questionnaire. To reduce recall bias, we will use data collected at the first interview (baseline) to measure this outcome.

Outcome measures

Outcome measures
Measure
SC/ST Girls in Intervention Village Cluster
n=625 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
SC/ST Girls in Control Village Cluster
n=566 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Number of Participants Entering Into 8th Standard [Start Secondary School]
580 Participants
516 Participants

SECONDARY outcome

Timeframe: May-August 2016 (cohort one) and May-August 2017 (cohort two)

This outcome will be assessed using data collected from all study participants at end-line, using the face-to-face questionnaire.

Outcome measures

Outcome measures
Measure
SC/ST Girls in Intervention Village Cluster
n=912 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
SC/ST Girls in Control Village Cluster
n=876 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Number of Participants Passing 10th Standard [Pass 10th Standard Exam]
518 Participants
530 Participants

SECONDARY outcome

Timeframe: May-August 2016 (cohort one) and May-August 2017 (cohort two)

This outcome will be assessed using data collected from all study participants at end-line, using the self-completed questionnaire.

Outcome measures

Outcome measures
Measure
SC/ST Girls in Intervention Village Cluster
n=912 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
SC/ST Girls in Control Village Cluster
n=876 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Number of Participants Having Sexual Debut [by Trial End Line]
64 Participants
53 Participants

SECONDARY outcome

Timeframe: May-August 2016 (cohort one) and May-August 2017 (cohort two)

This outcome will be assessed using data collected from all study participants at end-line, using the face-to-face questionnaire.

Outcome measures

Outcome measures
Measure
SC/ST Girls in Intervention Village Cluster
n=912 Participants
All SC/ST girls in final year of primary school living in intervention villages eligible for study enrolment.
SC/ST Girls in Control Village Cluster
n=876 Participants
All SC/ST girls in final year of primary school living in control villages eligible for study enrolment
Number of Participants Married and Co-habiting With Husband [by Trial End Line]
43 Participants
46 Participants

Adverse Events

SC/ST Girls in Intervention Village Cluster

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

SC/ST Girls in Control Village Cluster

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr Tara Beattie

London School of Hygiene and Tropical Medicine

Phone: 0044 (0)2079272613

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place