Feasibility Trial Of Image Guided External Beam Radiotherapy With Or Without High Dose Rate Brachytherapy Boost In Men With Intermediate-Risk Prostate Cancer
NCT01982786 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 57
Last updated 2026-04-13
Summary
This research is being done because investigators involved in this study would like to compare image guided external beam radiation therapy (IGRT) to IGRT plus HDR brachytherapy boost to see which treatment is better and what the side effects of treatment are.
Conditions
Interventions
- RADIATION
-
Image guided external beam radiotherapy with or without brachytherapy boost
image guided external beam radiotherapy (IGRT) or IGRT with high dose rate (HDR) brachytherapy boost
- RADIATION
-
Brachytherapy
Brachytherapy boost
Sponsors & Collaborators
-
Canadian Cancer Trials Group
lead NETWORK
Principal Investigators
-
Eric Vigneault · CHUQ - Hotel Dieu de Quebec, Quebec QC
-
Douglas Loblaw · Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto On
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-04-22
- Primary Completion
- 2016-07-05
- Completion
- 2018-10-19
Countries
- Canada
Study Locations
More Related Trials
-
Hypofractionated Intensity Modulated Radiation Therapy Plus Hormonal Therapy in Patients With High Risk Prostate Cancer
NCT02107287 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy Study of Hypofractionated Radiotherapy and Androgen Deprivation Therapy for Prostate Cancer
NCT01505075 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer
NCT05313815 ·Status: RECRUITING ·Phase: NA
-
SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer
NCT04861415 ·Status: RECRUITING ·Phase: NA
-
Hypofractionated Stereotactic Body Radiation Therapy as a Boost to the Prostate
NCT01508390 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Phase II Study to Evaluate Conventional Radiation Therapy Followed by Radiosurgical Boost in Clinically Localized Prostate Cancer
NCT01618851 ·Status: UNKNOWN ·Phase: NA
-
Radical Radiotherapy by External Beam Radiation Versus Radical Radiotherapy With Temporary Iridium Implant Plus External Beam Radiation in Carcinoma of the Prostate
NCT00548600 ·Status: COMPLETED ·Phase: PHASE3
-
Toxicity Comparison Between Hypofractionated Radiotherapy With HDR Brachytherapy Boost Versus Standard Treatment
NCT01851018 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Comparing Hypofractionated Radiotherapy Boost to Conventionally Fractionated
NCT02300389 ·Status: COMPLETED ·Phase: NA
-
Focal Versus Whole Gland High Dose-Rate Brachytherapy (HDR-BT) Boost to External Beam Radiotherapy in Localized Prostate Cancer: A Phase 2 Randomized Trial
NCT07300566 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Pelvic Nodes Ultra-Hypo vs Conventionally Fractionated IMRT With HDR Boost in Prostate Cancer.
NCT05820633 ·Status: SUSPENDED ·Phase: NA
-
MRI Assisted Focal Boost With HDR Monotherapy for Prostate Cancer Patients
NCT02623933 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients
NCT02303327 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Radiation Therapy in Treating Patients With Stage II or Stage III Prostate Cancer
NCT00091390 ·Status: COMPLETED ·Phase: PHASE2
-
Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer
NCT03367702 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Two-Fraction Ultrahypofractionated Radiotherapy With Focal Boost for Intermediate Risk, Localized Prostate Cancer
NCT06518226 ·Status: RECRUITING ·Phase: NA
-
EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer
NCT04465500 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Radiation Therapy in Treating Patients With Stage I or Stage II Prostate Cancer
NCT00002703 ·Status: COMPLETED ·Phase: PHASE3
-
Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer
NCT03987386 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Prostate Boost Irradiation With Stereotactic Body RT (SBRT)
NCT03380806 ·Status: UNKNOWN ·Phase: PHASE2
-
Radiation Therapy in Combination With Brachytherapy for Clinically Localized, Intermediate Risk Prostate Cancer
NCT02280356 ·Status: COMPLETED ·Phase: PHASE2
-
Single Fraction HDR Brachytherapy Plus Hypofractionated EBRT for Low-risk Prostate Cancer: Phase II Trial
NCT02283346 ·Status: UNKNOWN ·Phase: PHASE2
-
Hypofractionated Accelerated Radiotherapy for Low Risk Localized Prostate Cancer
NCT01578902 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy Study of Dose-escalated Hypofractionated Radiotherapy For Prostate Cancer
NCT01146340 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Functional Image-Guided Carbon Ion Irradiation With Simultaneous Integrated Boost for Prostate Cancer
NCT05010343 ·Status: RECRUITING ·Phase: PHASE2