MedTrace Logo

The Radiation Metabolic Signature of Patient Undergoing Radiotherapy. A Pilot Study

NCT01975558 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2020-03-02

No results posted yet for this study

Summary

Rationale: Local radiotherapy applied in the treatment of tumors changes the metabolic profile in the exposed area and/or systemically and specific radiation biomarkers can be identified in the respective matrices.

Purpose: This is a pilot study to verify in humans the results obtained from two animal models exposed to ionizing gamma-radiation. The classification of patients results from the treatment volume of radiotherapy for cancer disease. Two patient groups with breast cancer undergoing high-dose radiotherapy are selected and compared to control group of age matched healthy women.

Conditions

Interventions

BIOLOGICAL

Sampling at baseline, one week after baseline, two weeks after baseline

BIOLOGICAL

Sampling at baseline, during radiotherapy and after

Sponsors & Collaborators

  • Insel Gruppe AG, University Hospital Bern

    lead OTHER

Principal Investigators

  • Kristina Loessl, MD · Dept. of Radiation Oncology, University Hospital, Inselspital Bern

Eligibility

Min Age
50 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-06-26
Primary Completion
2019-11-12
Completion
2019-11-12

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01975558 on ClinicalTrials.gov