A Phase Ⅰa Study of Remimazolam Tosylate in Healthy Volunteers
NCT01970072 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 79
Last updated 2018-01-31
Summary
The purpose of this study is to evaluate and compare the Pharmacokinetics/Pharmacodynamics and safety of Remimazolam Tosylate with midazolam in healthy volunteers
Conditions
- Healthy
Interventions
- DRUG
-
Remimazolam Tosylate
- DRUG
-
Midazolam
Sponsors & Collaborators
-
Jiangsu HengRui Medicine Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Bei Hu, Professor · Peiking Union Medical College Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-10-14
- Primary Completion
- 2014-06-20
- Completion
- 2014-06-20
Countries
- China
Study Locations
More Related Trials
-
Remimazolam Tosilate Sedation and Midazolam Sedation in Dental Patients
NCT04602845 ·Status: COMPLETED ·Phase: PHASE4
-
Phase I Trail for Intramuscular Administration of Midazolam Using An Autoinjector
NCT00534378 ·Status: COMPLETED ·Phase: PHASE1
-
Sedative Effect and Safety of Remimazolam Besylate in ARDS Patients
NCT05758597 ·Status: RECRUITING ·Phase: PHASE4
-
A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury
NCT02071407 ·Status: UNKNOWN ·Phase: PHASE4
-
The Study of Different Sedative Medications in Monitored Anesthesia Care During Eye Surgery With Local Anesthesia
NCT04018703 ·Status: UNKNOWN ·Phase: NA
-
A Study of the Safety and Pharmacokinetics of JNJ-38518168 in Japanese and Caucasian Male Participants and the Effect of JNJ-38518168 on the Blood Levels of Midazolam
NCT01442532 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison Between Remimazolam Tosilate and Midazolam in Elderly Patients Undergoing Gastrointestinal Endoscopy
NCT04656964 ·Status: COMPLETED ·Phase: NA
-
A Midazolam Drug Interaction Study With PF-04171327
NCT00987038 ·Status: COMPLETED ·Phase: PHASE1
-
Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users
NCT04110535 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation
NCT05447507 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU
NCT05480787 ·Status: UNKNOWN ·Phase: PHASE4
-
Study To Evaluate The Effect Of Multiple Doses of CTP-543 On The Pharmacokinetics Of Single Doses of Midazolam In Healthy Subjects
NCT05467709 ·Status: COMPLETED ·Phase: PHASE1
-
Step 1 of A Two-step Trial to Evaluate the Effectiveness and Safety of Remimazolam Besylate for Sedation in ICU Patients
NCT06124404 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Pharmacokinetics and Pharmacodynamics of Intranasal Dexmedetomidine in Healthy Subjects
NCT03293277 ·Status: UNKNOWN ·Phase: PHASE1
-
Effect of Remimazolam Use During Perioperative Period on Brain Waves and Postoperative Cognitive Function
NCT04601350 ·Status: COMPLETED ·Phase: NA
-
A Randomized Single-blind Clinical Trial of the Efficacy and Safety of Remimazolam in Painless Bronchoscopy
NCT04919174 ·Status: UNKNOWN ·Phase: PHASE4
-
Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy
NCT00869440 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
NCT05437497 ·Status: UNKNOWN ·Phase: NA
-
Premedication With Oral Midazolam in Patients Undergoing Rigid Cystoscopy: A Randomized, Double-blind, Placebo-controlled Trial
NCT00563069 ·Status: UNKNOWN ·Phase: NA
-
A Study in Healthy People to Test How Well Different Doses of BI 3000202 Are Tolerated and How They Affect the Way the Body Handles Midazolam
NCT06327256 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study in Healthy Subjects to Evaluate the Effect of IPI-145 on the Pharmacokinetics of Midazolam
NCT01925911 ·Status: COMPLETED ·Phase: PHASE1
-
The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal Anesthesia
NCT05935657 ·Status: UNKNOWN ·Phase: NA
-
Phase 1 Bioavailability Study of MELT-100 (Midazolam and Ketamine Sublingual) and IV Midazolam or Ketamine
NCT04485702 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Study To Characterize The Safety, Tolerability, PK And PK Of Repeat Doses Of PF-06648671 In Healthy Adults And Healthy Elderly Subjects
NCT02440100 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects
NCT03187015 ·Status: COMPLETED ·Phase: PHASE1