Botswana Combination Prevention Project

Summary

The BCPP study is designed to test the hypothesis that implementing an enhanced combination prevention package which includes provision of ART to all participants, regardless of CD4 count or HIV disease severity, will impact the HIV/AIDS epidemic by significantly reducing population-level, cumulative HIV incidence in a defined geographic area over a period of 3 years and will be cost-effective.

Conditions

• HIV

Interventions

OTHER

Combination Prevention

OTHER

Enhanced Care

Sponsors & Collaborators

• Botswana Harvard AIDS Institute Partnership

  collaborator OTHER

• Botswana Ministry of Health

  collaborator OTHER_GOV

• Harvard School of Public Health (HSPH)

  collaborator OTHER

• Tebelopele Voluntary Counseling and Testing Center

  collaborator UNKNOWN

• Centers for Disease Control and Prevention

  lead FED

Principal Investigators

• Janet S Moore, PhD · Centers for Disease Control and Prevention

• Myron Essex, DVM, PhD · Harvard School of Public Health (HSPH)

• Refeletswe Lebelonyane, MD · Botswana Ministry of Health

• Shenaaz El Halabi, MPH · Botswana Ministry of Health

• Joseph Makhema, MBChB, FRCP · Botswana Harvard AIDS Institute Partnership

• Shahin Lockman, MD, MS · Harvard School of Public Health (HSPH)

• Eric Tchetgen Tchetgen, PhD · Harvard School of Public Health (HSPH)

• Molly Pretorius Holme, MS · Harvard School of Public Health (HSPH)

• Pam Bachanas, PhD · Centers for Disease Control and Prevention

• Tafireyi Marukutira, MD · Centers for Disease Control and Prevention

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Model

PARALLEL

Eligibility

Min Age

16 Years

Max Age

64 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-10-30

Primary Completion

2018-07-26

Completion

2018-07-26

Countries

• Botswana