Trial Outcomes & Findings for Skilled Motor Training and tDCS to Improve Leg Function After Spinal Cord Injury (NCT NCT01962675)

NCT ID: NCT01962675

Last Updated: 2015-11-16

Results Overview

Measuring Ankle range of motion (ROM) first at Baseline and then up to 1 hour after intervention at the Midswing phase during Gait.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

15 participants

Primary outcome timeframe

Two times, 1) Baseline, and 2) Up to 1 hour after intervention.

Results posted on

2015-11-16

Participant Flow

One participant withdrew before assignment

Participant milestones

Participant milestones
Measure
Real tDCS - Sham tDCS
Real tDCS+skilled training Transcranial direct current stimulation + step training TDCS will be delivered to the motor cortical area in conjunction with skilled locomotor training Transcranial direct current stimulation + step training: Direct current stimulation of motor cortex with low stimulation intensity Step training: Stepping over specified soft foam obstacles Sham transcranial direct current stimulation + step training: Stepping over specified soft foam obstacles Sham tDCS+skilled training Sham (Non active) tDCS and skilled leg training. 'Sham transcranial direct current stimulation + step training Sham tDCS will be delivered to the motor cortical area in conjunction with skilled locomotor training Step training: Stepping over specified soft foam obstacles
Sham tDCS - Real tDCS
Sham tDCS+skilled training Sham (Non active) tDCS and skilled leg training. 'Sham transcranial direct current stimulation + step training Sham tDCS will be delivered to the motor cortical area in conjunction with skilled locomotor training Step training: Stepping over specified soft foam obstacles Real tDCS+skilled training Transcranial direct current stimulation + step training TDCS will be delivered to the motor cortical area in conjunction with skilled locomotor training Transcranial direct current stimulation + step training: Direct current stimulation of motor cortex with low stimulation intensity Step training: Stepping over specified soft foam obstacles
Overall Study
STARTED
7
7
Overall Study
COMPLETED
7
7
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Skilled Motor Training and tDCS to Improve Leg Function After Spinal Cord Injury

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Two times, 1) Baseline, and 2) Up to 1 hour after intervention.

Population: Study was to be PhD student dissertation. PI left institution. Months later PhD student withdrew without notice. Data were stored on computers and not accessible to PI. Computers were replaced by new lab director.

Measuring Ankle range of motion (ROM) first at Baseline and then up to 1 hour after intervention at the Midswing phase during Gait.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Two times, 1) Baseline, and 2) Up to 1 hour after intervention.

Population: Study was to be PhD student dissertation. PI left institution. Months later PhD student withdrew without notice. Data were stored on computers and not accessible to PI. Computers were replaced by new lab director.

Measuring Active motor threshold using single pulse transcranial magnetic stimulation (TMS) of Motor cortex M1 area

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Two times, 1) Baseline, and 2) Up to 1 hour after intervention.

Population: Study was to be PhD student dissertation. PI left institution. Months later PhD student withdrew without notice. Data were stored on computers and not accessible to PI. Computers were replaced by new lab director.

Change from baseline score of the time required to perform 10 m walking.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Two times, 1) Baseline, and 2) Up to 1 hour after intervention.

Population: Study was to be PhD student dissertation. PI left institution. Months later PhD student withdrew without notice. Data were stored on computers and not accessible to PI. Computers were replaced by new lab director.

Measuring the Time required to perform toe taps

Outcome measures

Outcome data not reported

Adverse Events

tDCS and Skilled Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Sham tDCS and Skilled Leg Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Edelle Field-Fote

Shepherd Center

Phone: 404-603-4274

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place