Trial Outcomes & Findings for Prognosis of Depression in the Elderly (PRODE). A Multicentre, Longitudinal Study of Elderly Depressed Patients. (NCT NCT01952366)

Results Overview

Relapse/recurrence of depression

Recruitment status

COMPLETED

Target enrollment

169 participants

Primary outcome timeframe

1 year after inclusion to the study

Results posted on

2026-04-13

Participant Flow

Participant milestones

Participant milestones
Measure	Depressed Patients Patients admitted to specialist health care service of old age psychiatry
Overall Study STARTED	169
Overall Study COMPLETED	138
Overall Study NOT COMPLETED	31

Reasons for withdrawal

Reasons for withdrawal
Measure	Depressed Patients Patients admitted to specialist health care service of old age psychiatry
Overall Study Death	22
Overall Study Withdrawal by Subject	9

Baseline Characteristics

Prognosis of Depression in the Elderly (PRODE). A Multicentre, Longitudinal Study of Elderly Depressed Patients.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Depressed Patients n=169 Participants Patients admitted to specialist health care service of old age psychiatry
Age, Categorical <=18 years	0 Participants n=193 Participants
Age, Categorical Between 18 and 65 years	6 Participants n=193 Participants
Age, Categorical >=65 years	163 Participants n=193 Participants
Age, Continuous	76.1 years STANDARD_DEVIATION 6.8 • n=193 Participants
Sex: Female, Male Female	123 Participants n=193 Participants
Sex: Female, Male Male	46 Participants n=193 Participants
Region of Enrollment Norway	169 participants n=193 Participants

PRIMARY outcome

Timeframe: 1 year after inclusion to the study

Population: Inpatients

Relapse/recurrence of depression

Outcome measures

Outcome measures
Measure	Depressed Patients n=146 Participants Patients admitted to specialist health care service of old age psychiatry
Depression	48 participants

PRIMARY outcome

Timeframe: Three years follow-up (mean follow-up time: 1167 days (SD=41)

We have described the course of depression after treatment in departments of old-age psychiatry at specialist healthcare services using assessments at one- and year follow-up. The patients were decribed in the following categories courses: Favourable/less favourable/unfavourable/unclassifiable.

Outcome measures

Outcome measures
Measure	Depressed Patients n=131 Participants Patients admitted to specialist health care service of old age psychiatry
Depression During Three Years Favourable course	24 Counts of participants
Depression During Three Years Less favourable course	55 Counts of participants
Depression During Three Years Unfaourable course	51 Counts of participants
Depression During Three Years Unclassifiable	1 Counts of participants

SECONDARY outcome

Timeframe: 1 year after inclusion to the study

One year after inclusion to the study, there will be a clinical assessment of the patient including a MMSE, if possible, and to evaluate if the patients have dementia.

Outcome measures

Outcome measures
Measure	Depressed Patients n=146 Participants Patients admitted to specialist health care service of old age psychiatry
Number of Patients With a Diagnosis of Dementia (According to ICD-10) One Year After Inclusion to the Study.	23 Participants

SECONDARY outcome

Timeframe: 3 years after inclusion to the study (mean time 1167 days, SD 41).

3 years after inclusion to the study there was an assessment inluding all available information on cognition; i.e. information from previous follow-ups, clinical or telephone assessment of cognition using Mini Mental Status Examination (MMSE, clinical or telephone-version), and information from next-of-kin or caregivers including the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) and The Clinical Dementia Rating (CDR). Three Senior Consultants with a PhD then used all available information to diagnose dementia according to the ICD-10 classification.

Outcome measures

Outcome measures
Measure	Depressed Patients n=131 Participants Patients admitted to specialist health care service of old age psychiatry
Number of Patients With a Diagnosis of Dementia (According to ICD-10) Three Years After Inclusion to the Study.	40 Count of participants

Adverse Events

Depressed Patients

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. PhD Tom Borza

Sykehuset Innlandet

Phone: +47 91834607

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place