Trial Outcomes & Findings for RETeval Study for Diabetic Retinopathy (NCT NCT01950663)

NCT ID: NCT01950663

Last Updated: 2017-06-12

Results Overview

Accuracy will be reported as count of participants with referral status correctly identified, sensitivity, and specificity, with ETDRS photography and reading as the gold standard.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

468 participants

Primary outcome timeframe

During a single visit, implicit time, measured by the RETeval device, and ETDRS photography, will be performed to support the analysis of the accuracy of the RETeval device.

Results posted on

2017-06-12

Participant Flow

Participant milestones

Participant milestones
Measure
RETeval
RETeval is a new handheld device intended to detect vision threatening diabetic retinopathy by measuring the response of the retina to a flash of light. RETeval: RETeval is a new handheld device intended to detect vision threatening diabetic retinopathy by measuring the response of the retina to a flash of light.
Overall Study
STARTED
468
Overall Study
COMPLETED
467
Overall Study
NOT COMPLETED
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

RETeval Study for Diabetic Retinopathy

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
RETeval
n=467 Participants
RETeval is a new handheld device intended to detect vision threatening diabetic retinopathy by measuring the response of the retina to a flash of light. RETeval: RETeval is a new handheld device intended to detect vision threatening diabetic retinopathy by measuring the response of the retina to a flash of light.
Age, Continuous
61 years
STANDARD_DEVIATION 11 • n=99 Participants
Sex: Female, Male
Female
58 Participants
n=99 Participants
Sex: Female, Male
Male
409 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
9 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
458 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Race (NIH/OMB)
American Indian or Alaska Native
24 Participants
n=99 Participants
Race (NIH/OMB)
Asian
2 Participants
n=99 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
Race (NIH/OMB)
Black or African American
184 Participants
n=99 Participants
Race (NIH/OMB)
White
243 Participants
n=99 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
Race (NIH/OMB)
Unknown or Not Reported
14 Participants
n=99 Participants
Region of Enrollment
United States
467 participants
n=99 Participants

PRIMARY outcome

Timeframe: During a single visit, implicit time, measured by the RETeval device, and ETDRS photography, will be performed to support the analysis of the accuracy of the RETeval device.

Population: Participants with gradeable fundus photos and RETeval measurements

Accuracy will be reported as count of participants with referral status correctly identified, sensitivity, and specificity, with ETDRS photography and reading as the gold standard.

Outcome measures

Outcome measures
Measure
RETeval
n=401 Participants
RETeval is a new handheld device intended to detect vision threatening diabetic retinopathy by measuring the response of the retina to a flash of light. RETeval: RETeval is a new handheld device intended to detect vision threatening diabetic retinopathy by measuring the response of the retina to a flash of light.
Per Patient Referral Accuracy
318 Participants

Adverse Events

RETeval

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Stephen R. Fransen

Dean McGee Eye Institute / University of Oklahoma Health Sciences Center

Phone: 405-271-1092

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place