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Evaluation of the Inhibitory Effect of 5 Anti-Histamines in Urticaria

NCT01940393 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2014-02-19

No results posted yet for this study

Summary

The antihistamines with inhaled steroids are the cornerstone on the symptomatic therapy in the management of patients with rhinitis and the first line of treatment in patients with urticaria. Currently, the use of antihistamines has become popular due to its excellent safety profile and clinical efficacy, however to the investigators knowledge, there are no studies about the pharmacokinetic and pharmacodynamic effects of these drugs in patients of tropical Latin America. The investigators main interest is to evaluate if skin test inhibition correlates with the clinical effect of five anti-histamines.

Conditions

  • Urticaria

Interventions

DRUG

Cetirizine

Drug administration

DRUG

Desloratadine

Drug Administration

DRUG

Fexofenadine

Drug administration

DRUG

Ebastine

Drug administration

DRUG

Bilastine

Drug administration

Sponsors & Collaborators

  • Grupo de Alergología Clínica y Experimental

    lead OTHER

Principal Investigators

  • Jorge Sánchez, M.D · IPS Universitaria, University of Antioquia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2013-12-31
Completion
2014-01-31

Countries

  • Colombia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01940393 on ClinicalTrials.gov