Trial to Improve Access to PMTCT Services and Reduce HIV Transmission From Mother to Child

Summary

The purpose of this study is to determine the effectiveness, cost-effectiveness, feasibility and acceptability of an enhanced community health worker (CHW) intervention and outreach system to improve antenatal care and PMTCT uptake and retention, and to decrease mother-to-child HIV transmission.

Conditions

• Mother-to-child Transmission of HIV
• Pregnancy

Interventions

OTHER

Enhanced CHW intervention

The CHW employed in this study are a health worker cadre that already exists in the Tanzanian public-sector health system, so-called "home-base carers" (or HBC). The HBC in this study are supervised by another existing cadre, so-called "community-based health care workers" (or CBHC). The CBHC are clinic-based and are charged to organize community outreach activities in the Tanzanian public-sector health systems. The CBHC (1-2 per clinic) are also active in the control arm; in this intervention arm, there role is changed: they are actively supervising a large number of CHW. Per street (or mtaa), 1-2 CHW are assigned to carry out the enhanced CHW intervention.

OTHER

Standard of care

The standard of care in the Tanzanian health care system does not include any CHW intervention to enhance ANC and PMTCT uptake and retention. The only community-based intervention are PMTCT follow-up organized by a health worker cadre who works out of ANC and primary care clinics (so-called CBHC).

Sponsors & Collaborators

• Management and Development for Health, Tanzania

  collaborator UNKNOWN

• Elton John AIDS Foundation

  collaborator OTHER

• Comic Relief UK

  collaborator UNKNOWN

• Harvard School of Public Health (HSPH)

  lead OTHER

Principal Investigators

• Till Bärnighausen, MD ScD · Harvard School of Public Health (HSPH)

• Guerino Chalamilla, MD PhD · Management and Development for Health

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

PARALLEL

Eligibility

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-01-31

Primary Completion

2014-04-30

Completion

2014-04-30

Countries

• Tanzania

Study Locations