CPI-613 in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer
NCT01931787 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2018-07-03
Summary
This pilot clinical trial studies CPI-613 (6,8-bis\[benzylthio\]octanoic acid) in treating patients with relapsed or refractory small cell lung cancer. CPI-613 may interfere with the growth of tumor cells and may be an effective treatment for small cell lung cancer.
Conditions
- Recurrent Small Cell Lung Cancer
Interventions
- DRUG
-
6,8-bis(benzylthio)octanoic acid
Given IV
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
Jimmy Ruiz · Wake Forest University Health Sciences
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-10-31
- Primary Completion
- 2015-12-31
- Completion
- 2015-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Bcl-2 Antisense Oligodeoxynucleotide G3139 and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer
NCT00005032 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
PH 1 Evaluation Of Oral CI-1033 In Combination With Paclitaxel/ Carboplatin As 1st Line Chemotherapy In NSCLC Patients
NCT00174356 ·Status: COMPLETED ·Phase: PHASE1
-
Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer
NCT01533181 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Nab-paclitaxel in Sensitive and Refractory Relapsed SCLC
NCT03219762 ·Status: UNKNOWN ·Phase: PHASE2
-
Irinotecan and Carboplatin in Treating Patients With Metastatic or Recurrent Small Cell Lung Cancer
NCT00387660 ·Status: COMPLETED ·Phase: PHASE2
-
Chloroquinoxaline Sulfonamide in Treating Patients With Small Cell Lung Cancer
NCT00008372 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients With Stage III/IV and Relapsed NSCLC
NCT00001450 ·Status: COMPLETED ·Phase: PHASE2
-
Intratumoral Cisplatin for Resectable NSCLC
NCT04809103 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancer
NCT03850067 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Paclitaxel, Carboplatin, and Gemcitabine Versus Gemcitabine and Vinorelbine for Non-Small Cell Lung Cancer
NCT00193362 ·Status: COMPLETED ·Phase: PHASE3
-
Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT01413750 ·Status: TERMINATED ·Phase: PHASE2
-
Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer
NCT01803269 ·Status: TERMINATED ·Phase: PHASE2
-
Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer
NCT05450965 ·Status: RECRUITING ·Phase: PHASE2
-
Obatoclax Mesylate and Topotecan Hydrochloride in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer or Advanced Solid Tumors
NCT00521144 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy in Extensive-Stage Small Cell Lung Cancer
NCT05309629 ·Status: COMPLETED ·Phase: PHASE2
-
7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer
NCT00098956 ·Status: COMPLETED ·Phase: PHASE2
-
Penfluridol for Relapsed/Refractory Small Cell Cancers
NCT07206563 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer
NCT00004126 ·Status: COMPLETED ·Phase: PHASE2
-
Pazopanib in Relapsed and Refractory Small Cell Lung Cancer
NCT01713296 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 2 Study of S-1 in Combination With Cisplatin as 1st Line Therapy in Advanced Non-Small Cell Lung Cancer
NCT00651833 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of OSI-211 (Liposomal Lurtotecan) to Treat Recurrent Small Cell Lung Cancer
NCT00046787 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer
NCT03613753 ·Status: UNKNOWN ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00005646 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Carboplatin/Paclitaxel With or Without Investigational Drug (CS-7017) in Subjects With Metastatic Non-small Cell Lung Cancer
NCT00806286 ·Status: COMPLETED ·Phase: PHASE2
-
Bronchoscopic Intratumoral Chemotherapy for Small Cell Lung Cancer (SCLC)
NCT01487499 ·Status: TERMINATED ·Phase: PHASE3