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Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled Trial

NCT01931215 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 180

Last updated 2017-11-21

No results posted yet for this study

Summary

Analgesia after cesarean section is still not satisfactory for many women. Even if pain reduction is sufficient with the technique of intrathecal morphine injection, side effects such as nausea and pruritus are common.

Since several years, an alternative technique has been studied, the "transversus abdominis plane (TAP)"-block. Here a local anesthetic is injected in the abdominal wall muscles, and this has been shown to give a similar analgesic effect compared to intrathecal morphine, with potentially less side effects.

With this study, we want to evaluate if the TAP-block yields indeed less side effects when compared with intrathecal morphine.

The study will be a prospective study with the patients randomized to either a group with intrathecal morphine or a group with TAP-block.

Conditions

  • Postoperative Pain

Interventions

OTHER

spinal anesthesia with intrathecal morphine

in addition to the standard spinal anesthesia drugs (bupivacaine and fentanyl), morphine is added

OTHER

TAP-block with ropivacaine and clonidine

Sponsors & Collaborators

  • Domitille Dereu

    collaborator UNKNOWN

  • Benno Rehberg-Klug

    lead OTHER

Principal Investigators

  • Domitille Dereu, MD · HUG

  • Domitille Dereu, MD · HUG

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-09-30
Primary Completion
2017-03-31
Completion
2017-08-28

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01931215 on ClinicalTrials.gov