MedTrace Logo

Ultrasound Characterization of Ovarian Follicle Dynamics in Women With Amenorrhea

NCT01927432 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 73

Last updated 2024-02-09

No results posted yet for this study

Summary

In women with regular menstrual cycles, antral follicles have been shown to grow in synchronous cohorts, called waves, 2-3 times in a menstrual cycle. It is unknown whether these waves of follicle growth also occur in women with amenorrhea or if there is abnormal/absent follicle growth. Further, oligo- or amenorrhea has been associated with metabolic disturbances, such as over- or under-nutrition, central obesity and insulin resistance. Yet, mechanisms whereby metabolic factors influence folliculogenesis in women are poorly understood. To understand potential mechanisms, the investigators plan to characterize follicle growth dynamics in women with or without regular menstrual cycles and identifying key metabolic differences in these women which may be important in normal follicle development and fertility.

Conditions

  • Oligomenorrhea
  • Amenorrhea
  • Polycystic Ovary Syndrome (PCOS)

Sponsors & Collaborators

Principal Investigators

  • Marla E. Lujan, PhD · Cornell University

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2021-09-30
Completion
2021-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01927432 on ClinicalTrials.gov