Trial Outcomes & Findings for Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy (NCT NCT01917513)

NCT ID: NCT01917513

Last Updated: 2018-01-23

Results Overview

The percentage of patients with at least one adenoma or serrated lesion in the G-EYE™ group will be compared to the Standard group

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

1000 participants

Primary outcome timeframe

Approximalty following 14 days (histology results)

Results posted on

2018-01-23

Participant Flow

Participant milestones

Participant milestones
Measure
Standard Colonoscopy
Patients in this group underwent standard high definition colonoscopy
G-EYE™ Colonoscopy
Patients in this group underwent G-EYE™ high definition colonoscopy using using an insufflated balloon during withdrawal
Overall Study
STARTED
502
498
Overall Study
COMPLETED
407
396
Overall Study
NOT COMPLETED
95
102

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Standard Colonoscopy
n=396 Participants
Patients in this group underwent standard high definition colonoscopy
G-EYE™ Colonoscopy
n=407 Participants
Patients in this group underwent G-EYE™ high definition colonoscopy using using an insufflated balloon during withdrawal
Total
n=803 Participants
Total of all reporting groups
Age, Continuous
65.2 years
STANDARD_DEVIATION 8.79 • n=99 Participants
65.4 years
STANDARD_DEVIATION 8.92 • n=107 Participants
65.3 years
STANDARD_DEVIATION 8.85 • n=206 Participants
Sex: Female, Male
Female
173 Participants
n=99 Participants
204 Participants
n=107 Participants
377 Participants
n=206 Participants
Sex: Female, Male
Male
223 Participants
n=99 Participants
203 Participants
n=107 Participants
426 Participants
n=206 Participants

PRIMARY outcome

Timeframe: Approximalty following 14 days (histology results)

The percentage of patients with at least one adenoma or serrated lesion in the G-EYE™ group will be compared to the Standard group

Outcome measures

Outcome measures
Measure
Standard Colonoscopy
n=392 Participants
Patients in this group underwent standard high definition colonoscopy
G-EYE™ Colonoscopy
n=404 Participants
Patients in this group underwent G-EYE™ high definition colonoscopy using using an insufflated balloon during withdrawal
Detection Rate of Adenomas and Serrated Lesions
147 Participants
194 Participants

SECONDARY outcome

Timeframe: Up to 14 days (histology results)

The secondary outcome is a composite-each of the measured parameters will be reported as a single value for each arm

Outcome measures

Outcome data not reported

Adverse Events

G-EYE™ Colonoscopy

Serious events: 2 serious events
Other events: 0 other events
Deaths: 0 deaths

Standard Colonoscopy

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
G-EYE™ Colonoscopy
n=502 participants at risk
G-EYE™ colonoscopy G-EYE™ colonoscopy: G-EYE™ colonoscopy
Standard Colonoscopy
n=498 participants at risk
Standard Colonoscopy Standard Colonoscopy: Standard Colonoscopy
Gastrointestinal disorders
obstructive sigmoid tumor
0.20%
1/502
0.00%
0/498
Cardiac disorders
an irregular heart rate and bradycardia prior to the initiation of the procedure
0.20%
1/502
0.00%
0/498

Other adverse events

Adverse event data not reported

Additional Information

Prof. Ralf Kiesslich

Helios Dr. Horst Schmidt Kliniken, Wiesbaden, Germany

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place