Differences in Response to the Flu Vaccine Among Adults With HIV and Without HIV in Uganda
NCT01916759 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 63
Last updated 2014-04-23
Summary
To use a systems biological approach to study the molecular signatures of innate and adaptive responses to vaccination in a HIV infected versus uninfected adult population in Kampala, Uganda.
Conditions
Interventions
- DRUG
-
Seasonal trivalent inactivated influenza vaccine (Vaxigrip®)
Administer seasonal trivalent inactivated influenza vaccine (Vaxigrip®) and collect blood specimens at 0, 1, 3, 7, 14, 28 and 100 days following vaccination.
Sponsors & Collaborators
-
Makerere University
collaborator OTHER -
Emory University
lead OTHER
Principal Investigators
-
Saad B Omer, MBBS,MPH,PhD · Emory Unversity
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-06-30
- Primary Completion
- 2013-12-31
- Completion
- 2014-03-31
Countries
- Uganda
Study Locations
More Related Trials
-
Immunogenicity Study of the Influenza Vaccine in Adults
NCT00258934 ·Status: COMPLETED ·Phase: PHASE2
-
Surveillance of Influenza Virus Shedding and Immunologic Response in Immunocompromised Children and Young Adults
NCT00998803 ·Status: COMPLETED
-
Evaluation of Influenza-Specific Immune Responses in Children and Adults During the 2010-2011 Influenza Season in the U.S.
NCT01262079 ·Status: COMPLETED
-
Safety and Immunogenicity of Co-administration of Candidate Influenza Vaccine MVA-NP+M1 and Viroflu® Seasonal Influenza Vaccine
NCT02014168 ·Status: TERMINATED ·Phase: PHASE1
-
Impact of FLU Vaccination on Nasal Resident Memory Immune Responses and Peripheral Respiratory-tropic Memory Immune Responses
NCT06824779 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Influenza Vaccine Elicited Immune Response in Immunocompromised Patients
NCT06738082 ·Status: COMPLETED
-
Kinetics of the Immune Response to Inactivated Influenza Vaccine in Healthy Adults
NCT03743688 ·Status: COMPLETED
-
Routes of Immunization and Flu Immune Responses
NCT01707602 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Influenza Immunity in Children
NCT02559505 ·Status: COMPLETED ·Phase: NA
-
Mucosal and Systemic Immunity After Viral Challenge of Healthy Volunteers Vaccinated With Inactivated Influenza Vaccine Via the Intranasal Versus Intramuscular Route
NCT03845231 ·Status: COMPLETED ·Phase: PHASE2
-
Revealing Protective Immunity to Influenza Using Systems Immunology
NCT06501963 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Assess the Safety and Efficacy of a New Influenza Candidate Vaccine MVA-NP+M1 In Healthy Adults
NCT00993083 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Responses to Influenza A H1N1/09 Immunization in High-risk Patients
NCT01022905 ·Status: COMPLETED ·Phase: PHASE4
-
Improving Immunogenicity of Influenza Vaccine in HIV Infected Individuals
NCT01262846 ·Status: COMPLETED ·Phase: PHASE4
-
The Impact of Imprinting and Repeated Influenza Vaccination on Adaptive Immunity, Transcriptomics, and Metabolomics
NCT03686514 ·Status: TERMINATED ·Phase: PHASE4
-
Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya
NCT01810731 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Understanding Immunity to the Flu Vaccine in COVID-19 Patients
NCT04579588 ·Status: RECRUITING
-
Immunogenicity and Safety of the Seasonal Flu Vaccine in Elderly and in SOT Recipients
NCT02746783 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Systems Biology of Influenza A (H5N1) Virus Monovalent Vaccine With and Without Adjuvant System 03 (AS03)
NCT01910519 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Effectiveness of Vaccination With 2009 H1N1 Vaccines During Influenza Season 2010-11
NCT01206114 ·Status: COMPLETED
-
Rapid Evaluation of Pandemic H1N1 Influenza Vaccine in Adults With HIV
NCT01002040 ·Status: COMPLETED ·Phase: PHASE4
-
Incidence of H1N1v Influenza-like Illness and Risk Factors for Serious Influenza Forms in HIV Infected Patients
NCT01039220 ·Status: COMPLETED ·Phase: NA
-
Response of Older Adults to Influenza Vaccination With Regard to Cytomegalovirus (CMV) Status
NCT00442975 ·Status: COMPLETED ·Phase: PHASE4
-
The Objectives of This Study Are Study of the Reactogenicity, Safety and Immunogenicity of Flu-M Inactivated Split Influenza Vaccine in Volunteers Aged 18-60 Years
NCT05126979 ·Status: COMPLETED ·Phase: PHASE1
-
Influenza Vaccine Responses as a Means of Assessing Immune Competence in Chimeric Kidney/Stem Cell Transplant Recipients
NCT02623075 ·Status: COMPLETED