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Viral Testing and Biomarkers to Reduce Antibiotic Use for Respiratory Infections

NCT01907659 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2014-07-02

No results posted yet for this study

Summary

This trial is a pilot study to determine the feasibility of a randomized clinical trial comparing a treatment algorithm consisting of a limited number of clinical parameters, rapid molecular viral diagnostics, and serum procalcitonin testing to standard of care for directing antibiotic use in patients with non-pneumonic lower respiratory tract infection. The reduction in antibiotic use in those subjects randomized to the treatment algorithm compared to those randomized to standard care will be determined.

Conditions

Interventions

OTHER

Release of test results

Subjects will be randomized to have viral testing and serum PCT results released or no additional testing performed other than that ordered as standard of care

Sponsors & Collaborators

  • Rochester General Hospital

    collaborator OTHER

  • University of Rochester

    lead OTHER

Principal Investigators

  • Ann R Falsey, MD · University of Rochester

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2014-06-30
Completion
2014-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01907659 on ClinicalTrials.gov