N-acetylcysteine (NAC) for Improving Cognitive Dysfunction in Schizophrenia
NCT01885338 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2015-06-04
Summary
This study will evaluate the effect of the dietary supplement N-acetylcysteine (NAC) on electrophysiologic (EEG) markers related to cognition, as well as performance on psychological tests measuring cognition. The primary hypothesis is that participants treated with NAC will show improvements in cognitive function, as measured by EEG and performance-based tests.
Conditions
Interventions
- DRUG
-
N-acetylcysteine (NAC)
- DRUG
-
Inactive placebo capsule
Sponsors & Collaborators
-
VISN 22 Mental Illness Research, Education, and Clinical Center
collaborator FED -
American Psychiatric Foundation
collaborator UNKNOWN -
VA Greater Los Angeles Healthcare System
lead FED
Principal Investigators
-
Stephen R Marder, M.D. · VA Greater Los Angeles
-
Michael C Davis, M.D., Ph.D. · VA Greater Los Angeles
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-06-30
- Primary Completion
- 2014-05-31
- Completion
- 2014-05-31
Countries
- United States
Study Locations
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