CMV Glycoprotein B (gB) Vaccine Long Term Antibody Response
NCT01883206 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48
Last updated 2017-10-27
Summary
The purpose of this study is to see how well the antibody levels found months to years after patients entered a previous randomised placebo-controlled trial of a glycoprotein B vaccine against cytomegalovirus have persisted and to have the previous samples retested using different methods which have been further developed in different laboratories.
Also, to prepare monoclonal antibodies from the B lymphocytes of these patients and define their strength. If potent antibodies are identified, the investigators would like to consider developing them further to see if they can protect future transplant patients against cytomegalovirus.
Conditions
- Viraemia
Sponsors & Collaborators
-
University College, London
lead OTHER
Principal Investigators
-
Paul D Griffiths · UCL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-09-30
- Primary Completion
- 2016-02-29
- Completion
- 2016-02-29
Countries
- United Kingdom
Study Locations
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