Circulating Melanoma Cells in Metastatic Patients Treated With Selective BRAF Inhibitors
NCT01878396 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2016-10-03
Summary
The purpose of this study, is to evaluate Circulating Melanoma Cell (CMC) changes in Metastatic Melanoma (MM) patients, undergoing treatment with selective inhibitors of mutated BRAF.
Conditions
Interventions
- DRUG
-
Anti-B-RAF
Sponsors & Collaborators
-
Janssen Diagnostics, LLC
collaborator INDUSTRY -
Istituto Oncologico Veneto IRCCS
lead OTHER
Principal Investigators
-
Paola Zanovello, Phd · Padua University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-12-31
- Primary Completion
- 2016-12-31
- Completion
- 2017-12-31
Countries
- Italy
Study Locations
More Related Trials
-
Phase 1 Safety and Tolerability of MEDI4736 in Combination With Dabrafenib and Trametinib or With Trametinib Alone
NCT02027961 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain
NCT02039947 ·Status: COMPLETED ·Phase: PHASE2
-
Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis
NCT02537600 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Dabrafenib+Trametinib in the Adjuvant Treatment of Stage III BRAF V600+ Melanoma After Complete Resection to Evaluate the Impact on Pyrexia Related Outcomes
NCT03551626 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma
NCT01153763 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma.
NCT00057616 ·Status: COMPLETED ·Phase: PHASE3
-
Relapse-Free Survival With Adjuvant Dabrafenib/Trametinib Therapy in Patients With BRAF V600-mutated Stage III/IV Melanoma
NCT06557291 ·Status: COMPLETED
-
A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain
NCT01266967 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or Trametinib
NCT02314143 ·Status: TERMINATED ·Phase: PHASE2
-
Study of the Variations of Albumin Level for Patients With Unresecable Stage IIIc or Stage IV Melanoma Treated by Anti BRAF and Anti MEK
NCT03553329 ·Status: COMPLETED
-
A Study is to Understand the Treatment Patterns for Immunotherapy Agents and BRAF/MEK Inhibitors Used in the Treatment of Advanced Melanoma
NCT03696069 ·Status: COMPLETED
-
A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma
NCT01320085 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the Efficacy and Safety of a Sequencing Schedule of Cobimetinib Plus Vemurafenib Followed by Immunotherapy With an Anti- PD-L1 Antibody in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma
NCT02902029 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Dabrafenib + Trametinib for AJCC Stage IIIB-C BRAF V600 Mutation Positive Melanoma
NCT01972347 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Utility of Novel BRAF Test for Melanoma
NCT01840527 ·Status: COMPLETED
-
A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases
NCT03625141 ·Status: COMPLETED ·Phase: PHASE2
-
Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma
NCT03352947 ·Status: COMPLETED ·Phase: PHASE2
-
Melanoma Metastasized to the Brain and Steroids
NCT03563729 ·Status: RECRUITING ·Phase: PHASE2
-
Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma
NCT07223411 ·Status: RECRUITING
-
Dabrafenib and Trametinib for BRAF-inhibitor Pretreated Patients
NCT02296996 ·Status: COMPLETED ·Phase: PHASE2
-
Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites
NCT01978236 ·Status: TERMINATED ·Phase: PHASE2
-
Phase I Safety and Dosimetry Study in Patients With Confirmed Metastatic Melanoma
NCT00747825 ·Status: TERMINATED ·Phase: PHASE1
-
Anti-CD20 (Cluster of Differentiation Antigen 20) Therapy to Treat Metastatic Melanoma
NCT01376713 ·Status: COMPLETED ·Phase: PHASE2
-
Study of MDX-010 in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
NCT00729950 ·Status: COMPLETED ·Phase: PHASE1
-
Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma
NCT02581930 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2