Effect of Vitis Vinifera Extract on Oxidative Stress, Inflamatory Biomarkers and Hormones in High Trained Subjects
NCT01875497 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55
Last updated 2013-06-12
Summary
There is evidence that intense physical activity has a potential effect on thrombotic events due to catecholamine release. The hormones leptin and adiponectin have been used as markers of cardiovascular risk, but they are few and contradictory studies that relate physical training intensity and duration of high plasma concentrations of these hormones. The use of antioxidants, such as proanthocyanidins present in grapes, may help in reducing the undesirable effects of intense training.
Conditions
- Athletic Injuries
Interventions
- DIETARY_SUPPLEMENT
-
grape fruit (vitis vinifera) extract in capsule with 205 mg
Before the exercise the indivuduals intake only one capsule of the grape fruit extract with 205 mg. This dosage is free of contraindications according to others studies.
Sponsors & Collaborators
-
Rio de Janeiro State University
lead OTHER
Principal Investigators
-
J C Koury, PhD · Instituto de Nutrição Universidade do Estado do Rio de Janeiro - Brazil
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-01-31
- Primary Completion
- 2013-12-31
- Completion
- 2015-12-31
Countries
- Brazil
Study Locations
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