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CD34+ Stem Cell Infusion to Augment Graft Function

NCT01856582 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2019-11-22

Study results available
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Summary

The purpose of this study is to determine if infusing additional special donor cells will help to improve graft or immune function in previously transplanted children with immune deficiencies and bone marrow failures.

Conditions

  • Waning Donor Chimerism
  • Waning Immune Function
  • Primary Immunodeficiency Disease(s)
  • Bone Marrow Failure

Interventions

BIOLOGICAL

CD34+

CD34+ cells are selected using the CliniMACS System; without preparative regimen

Sponsors & Collaborators

  • Hoxworth Blood Center

    collaborator OTHER

  • Children's Hospital Medical Center, Cincinnati

    lead OTHER

Principal Investigators

  • Rebecca Marsh, MD · Children's Hospital Medical Center, Cincinnati

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-10-31
Primary Completion
2018-08-15
Completion
2018-08-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01856582 on ClinicalTrials.gov