Combining Doxycycline With Bone-Targeted Therapy in Patients With Metastatic Breast Cancer
NCT01847976 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 73
Last updated 2019-09-06
Summary
The purpose of this study is to see if women with bone metastases from breast cancer will benefit from the addition of doxycycline to their standard bone-targeted therapy. Participants will be asked to take 100 mg of Doxycycline orally twice a day for 12 weeks. Blood and tissue collection will further define the mechanism of the benefits if there are any.
Conditions
Interventions
- DRUG
-
Doxycycline
Participants will be asked to take 100 mg of Doxycycline by mouth twice a day for 12 weeks.
Sponsors & Collaborators
-
Canadian Breast Cancer Foundation
collaborator OTHER -
Ottawa Hospital Research Institute
lead OTHER
Principal Investigators
-
Mark Clemons, FRCP · The Ottawa Hospital Cancer Centre
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-08-31
- Primary Completion
- 2017-11-30
- Completion
- 2017-11-30
Countries
- Canada
Study Locations
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