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Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases

NCT01843413 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 33

Last updated 2025-07-20

No results posted yet for this study

Summary

This phase I/II trial studies the side effects and the best dose of stereotactic radiosurgery and to see how well it works in treating patients with large brain metastases. Radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue.

Conditions

  • Tumors Metastatic to Brain
  • Unspecified Adult Solid Tumor

Interventions

RADIATION

stereotactic radiosurgery

Undergo SRS

PROCEDURE

quality-of-life assessment

Ancillary studies

PROCEDURE

cognitive assessment

Ancillary studies

Sponsors & Collaborators

  • Case Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Samuel Chao, MD · Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-07-02
Primary Completion
2025-08-31
Completion
2025-08-31
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01843413 on ClinicalTrials.gov