A Study to Evaluate the Effect of Ranolazine on Postprandial Glucagon in Subjects With Type 2 Diabetes.
NCT01843127 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2014-03-31
Summary
To explore the mechanism of action of ranolazine as a potential treatment for type 2 diabetes mellitus (T2DM).
Conditions
Interventions
- DRUG
-
Ranolazine
- DRUG
- DRUG
-
Exenatide
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-04-30
- Primary Completion
- 2013-09-30
- Completion
- 2013-09-30
Countries
- United States
Study Locations
More Related Trials
-
Efficacy and Safety of Exenatide Once Weekly Suspension in Subjects With Type 2 Diabetes
NCT01652716 ·Status: COMPLETED ·Phase: PHASE3
-
A New Oral Treatment For Type II Diabetes Mellitus
NCT00111800 ·Status: COMPLETED ·Phase: PHASE2
-
Single-dose Study to Evaluate Safety, Tolerability, and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
NCT02715193 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Taspoglutide Versus Exenatide for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin, Thiazolidinedione or a Combination of Both.
NCT00717457 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of PN2034 in Insulin-Dependent Patients With Type 2 Diabetes
NCT00110864 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Exenatide as Monotherapy
NCT00381342 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Single or Repeated Doses of Glucagon in Participants With Diabetes
NCT02806973 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3143753 and LY3185643 in Healthy Participants
NCT02342314 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes
NCT02806960 ·Status: TERMINATED ·Phase: PHASE1
-
Use of Exenatide and Pramlintide to Decrease Post-prandial Hyperglycemia
NCT01269047 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Examine the Pharmacokinetics, Tolerability, Safety and Efficacy of Exenatide Once Weekly Suspension
NCT00894322 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Effects of Short-Term Exenatide Therapy in Newly Diagnosed Type 2 Diabetic Patients
NCT01270191 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Exenatide on 24-Hour Blood Glucose Profile Compared With Placebo in Patients With Type 2 Diabetes
NCT00241423 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Nasal Glucagon (LY900018) in Japanese Participants With Diabetes Mellitus
NCT03421379 ·Status: COMPLETED ·Phase: PHASE3
-
GALLANT 2 Tesaglitazar vs. Placebo
NCT00252772 ·Status: TERMINATED ·Phase: PHASE3
-
Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes
NCT00658021 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Technosphere® Insulin Versus Technosphere Powder (Placebo) in Insulin-Naive Subjects With Type 2 Diabetes Mellitus
NCT01451398 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly in Subjects With Type 2 Diabetes Mellitus (DURATION-5)
NCT00877890 ·Status: COMPLETED ·Phase: PHASE3
-
Addition Of Exenatide To Insulin Glargine In Type 2 Diabetes Mellitus
NCT00765817 ·Status: COMPLETED ·Phase: PHASE3
-
Assessment of Efficacy and Safety of Insuman Comb 25 Versus Novolin® 30R Twice Daily Over 24 Weeks in Type 2 Diabetes Patients With Insulin Therapy
NCT01353469 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of the Effect on Glucose Control and the Safety and Tolerability of AC2993 in Patients With Type 2 Diabetes Mellitus
NCT00044694 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Examine the Effect on Glucose Control and Safety/Tolerability of Exenatide Given Two Times a Day to Subjects With Type 2 Diabetes
NCT00111540 ·Status: COMPLETED ·Phase: PHASE3
-
First Time in Human Study Using GSK2330672
NCT01416324 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes
NCT02119819 ·Status: COMPLETED ·Phase: PHASE2
-
Exenatide Once Weekly, Cardiovascular Risk and Type-2 Diabetes
NCT02380521 ·Status: COMPLETED ·Phase: PHASE4