Value of PET-CT in Radiation Treatment Planning for Patients With Esophageal Cancer

NCT01836913 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2016-03-23

No results posted yet for this study

Summary

The RESPECT study is intended to prospectively assess the impact of PET/CT on the delineation of target volumes and to estimate the proportion of recurrences that could possibly be prevented by the use of PET/CT-based target volume, instead of CT-based. Patients will recieve radiotherapy using CT-based planning, but a PET/CT-based treatment plan will also be made. CT-based and PET/CT-based target volumes will be compared after treatment has been completed. If a locoregional recurrence takes place, the localisation will be compared to the CT-based and PET/CT based clinical target volumes (CTVs). If the local recurrence is located outside the CT-CTV but inside the PET/CT-CTV, the recurrence could possibly have been prevented with PET/CT-based radiotherapy.

Conditions

  • Esophageal Cancer

Sponsors & Collaborators

  • ZonMw: The Netherlands Organisation for Health Research and Development

    collaborator OTHER
  • University Medical Center Groningen

    lead OTHER

Principal Investigators

  • Johannes A Langendijk, PhD, MD · University Medical Center Groningen, Department of Radiation Oncology

  • John Th Plukker, PhD, MD · University Medical Center Groningen, Department of Surgical Oncology

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-05-31
Primary Completion
2012-04-30
Completion
2014-04-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01836913 on ClinicalTrials.gov