Effect of Oxytocin on Craving and Therapy Response
NCT01827332 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2017-01-02
Summary
The purpose of this study is to examine the impact of a medication called oxytocin on marijuana use and therapy response in people who frequently use marijuana.
Conditions
- Marijuana Dependence
Interventions
- DRUG
-
Oxytocin
Subjects will be administered 40 IUs of oxytocin nasal spray or matching placebo prior to two individual sessions of MET.
- DRUG
-
Saline
Subjects will be administered 40 IUs of oxytocin nasal spray or matching placebo prior to two individual sessions of MET.
Sponsors & Collaborators
-
Medical University of South Carolina
lead OTHER
Principal Investigators
-
Aimee L McRae-Clark, PharmD · Medical University of South Carolina
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-03-31
- Primary Completion
- 2015-06-30
- Completion
- 2016-07-31
Countries
- United States
Study Locations
More Related Trials
-
The Effects of ∆-9-THC and Naloxone in Humans
NCT01591629 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Marijuana Drug Discrimination and Self-Administration
NCT00943930 ·Status: COMPLETED
-
Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4
NCT00000252 ·Status: COMPLETED ·Phase: PHASE2
-
Oxytocin Effects on the Tolerance of Infidelity
NCT02733237 ·Status: COMPLETED ·Phase: NA
-
Deciphering the Role of Oxytocin in Motivation: an fMRI Study. Part II
NCT02652195 ·Status: UNKNOWN ·Phase: PHASE2
-
Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8
NCT00000256 ·Status: COMPLETED ·Phase: NA
-
Age-Related Effects of THC
NCT04294966 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Ovarian Hormones and Stress Induced Drug Craving
NCT02098434 ·Status: COMPLETED ·Phase: NA
-
Effects of Intranasal Oxytocin Administration on Social Influence Effects on Pain
NCT03060031 ·Status: COMPLETED ·Phase: PHASE1
-
Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7
NCT00000255 ·Status: COMPLETED ·Phase: PHASE2
-
Behavioral Pharmacology of THC and Beta-Myrcene
NCT05432284 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Dose-dependent Effects of Oxytocin on the Amygdala and Reward System
NCT03846739 ·Status: COMPLETED ·Phase: PHASE1
-
Opioid and Cannabinoid Interactions
NCT03705559 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Intranasal Oxytocin and Vasopressin on Social Behavior
NCT01296269 ·Status: UNKNOWN ·Phase: NA
-
Behavioral Pharmacology of THC and Alpha-pinene
NCT04130633 ·Status: COMPLETED ·Phase: PHASE1
-
Oxytocin Buffers Stress Response in Individuals With Impaired Coping Abilities
NCT01065610 ·Status: COMPLETED ·Phase: NA
-
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
NCT03221231 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
NCT00743119 ·Status: COMPLETED ·Phase: PHASE2
-
Behavioral Pharmacology of THC and D-limonene
NCT03609853 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Cannabis Extract on Acute Radicular Pain and on Analgesic Requirement
NCT04816994 ·Status: RECRUITING ·Phase: PHASE3
-
Characterization of the Pharmacodynamic Response to Vaped THC
NCT04340700 ·Status: WITHDRAWN ·Phase: PHASE3
-
The Effects of Marijuana on Orientation and Motor Coordination and Brain Metabolism in Regular Smokers of Marijuana
NCT00270803 ·Status: COMPLETED ·Phase: NA
-
Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders
NCT02824627 ·Status: COMPLETED ·Phase: PHASE2
-
Marijuana Cue-Reactivity & Seeking Behavior in Regular Cannabis Users
NCT03154580 ·Status: COMPLETED ·Phase: PHASE1
-
Tetrahydrocannabinol (THC) and Sleep
NCT03560934 ·Status: COMPLETED ·Phase: EARLY_PHASE1