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Effects of Simple Sodium Alignment on Clinical Outcomes

NCT01825590 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 148

Last updated 2016-02-24

No results posted yet for this study

Summary

A difference between dialysate and serum sodium concentration leads to diffusive sodium transfer across the dialyzer membrane. The consequences of diffusive sodium flux into the patient can be chronic sodium overload leading to overhydration, hypertension, cardiovascular disease, and other problems. Diffusive sodium flux out of the patient can lead to intradialytic blood pressure instability. A simple strategy for alignment of dialysate and serum sodium concentrations was implemented starting in April/May 2010 in order to minimize the problems particularly associated with chronic sodium overload.

Conditions

  • Complication of Hemodialysis

Interventions

OTHER

Dialysate and serum sodium concentration aligned

Sponsors & Collaborators

  • Renal Research Institute

    lead OTHER

Principal Investigators

  • Peter Kotanko, MD · Renal Research Institute

Eligibility

Min Age
18 Years
Max Age
88 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2014-08-31
Completion
2014-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01825590 on ClinicalTrials.gov