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A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)

NCT01817803 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2014-02-19

No results posted yet for this study

Summary

To compare the effectiveness and safety of diuretics add-on strategy in chronic heart failure patients

Conditions

  • Congestive Heart Failure

Interventions

DRUG

furosemide/no spironolactone

furosemide (doubling previous furosemide dose)

DRUG

metolazone/no spironolactone

metolazone (add 2.5mg qod)

DRUG

furosemid/spironolactone

furosemide (doubling previous furosemide dose)+spironolactone (doubling previous spironolactone dose or add 12.5mg BID if previous non-user)

DRUG

metolazone/spironolactone

metolazone (add 2.5mg qod)+ spironolactone (doubling previous spironolactone dose or add 12.5mg BID if previous non-user)

Sponsors & Collaborators

  • Yonsei University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2015-06-30
Completion
2015-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01817803 on ClinicalTrials.gov