Correlation Between Haptoglobin Phenotypes and Infectious and Other Complications in Cystic Fibrosis Patients
NCT01806025 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 142
Last updated 2016-07-28
Summary
Cystic Fibrosis is a genetic disease with variable severity, and a predisposition for lung infection. Usually severity is determined by the class of CF mutations, but even among patients with the same severity of mutations there is a variation of the severity of CF.
Haptoglobin has several types (phenotypes), one of them was found to be related to infectious complications.
In this study the investigators aim to find a correlation between Haptoglobin phenotypes in patients with CF and frequency of infectious complications.
To this end the investigators will collect serum from CF patients, and determine their Haptoglobin protein phenotype. The investigators will correlate Haptoglobin phenotype to retrospectively gathered data on infectious complications.
Conditions
Interventions
- OTHER
-
no intervention
Sponsors & Collaborators
-
Carmel Medical Center
lead OTHER
Principal Investigators
-
Michal Shteinberg, MD · Pulmonology Institute and CF Center, Carmel Medical Center
Eligibility
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-04-30
- Primary Completion
- 2015-01-31
- Completion
- 2015-01-31
Countries
- Israel
Study Locations
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