Prospective evAluatIon foR Inhalation Devices Study

Summary

ASTHMA:

Asthma is a chronic inflammatory disorder of the airways in which many different types of cells, and various cellular components. The chronic inflammation causes an increase of the over-responsiveness of the airways, which leads to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the early morning hours. These episodes, usually associated with widespread but variable block the airway, which is usually reversible either spontaneously or by treatment.

Asthma is one of the most common chronic diseases worldwide, posing significant social burden in both children and adults. It is estimated that about 300 million people currently suffer from asthma. The incidence of asthma is universal regardless of the level of development of the country. There is evidence that over the last 20 years the prevalence has increased significantly, specially in pediatric populations.

COPD:

Chronic Obstructive Pulmonary Disease (COPD) is a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States after heart disease, strokes and acute respiratory infections, while on an annual basis, the disease robs the lives of more than 3,000,000 people around us worldwide. The most worrying is that the impact has been steadily rising, and this dramatic increase in the frequency shows that by 2020 the disease will be the third leading cause of death. In Greece, 8.4% of the population suffers from COPD.

Smoking is the leading cause of COPD. However, not all smokers develop the clinical picture of COPD, suggesting that additional factors are involved in manifestation. Further investigation of risk factors for COPD, methods of reducing exposure to these agents and the molecular and cellular mechanisms involved in the pathogenesis remain a major area of research to develop effective treatments that will reduce or prevent the development the disease.

Conditions

• Asthma
• COPD

Sponsors & Collaborators

• Elpen Pharmaceutical Co. Inc.

  lead INDUSTRY

Principal Investigators

• Spyridon Papiris, MD, Professor · Professor of Pulmonology, Attikon University Hospital of Athens

• Athina Vlachou, MD · Private Office

• Areti Xifteri-Nikolinati, MD · Messini, Greece

• Georgios Efraimidis, MD · Plmonology Hospital of Patras, Greece

• Nikolaos Harokopos, MD · General hospital of Pyrgos, Peloponnese, Greece

• Dionysia Kalampoka, MD · Private Office, Patras, Greece

• Athanasia Christara, MD · Private Office, Korinthos, Greece

• Emmanouel Fothiantakis, MD · Private Office, Chaidari, Athens, Greece

• Elias Kainis, MD · Sotiria Pulmonogy Hospital of Athens

• Adamantia Liapikou, MD · Sotiria Pulmonary Hospital of Athens

• Xenophon Agelidis, MD · Attikon Hospital

• Antonios Kopanakis, MD · Thriasio General Hospital, Greece

• Konstantina Houliara, MD · Private office, Patisia, Athens, Greece

• Helen Adamou, MD · Nea Filadelfia, Athens, Greece

• George Kalfountzos, MD · Private office, Larissa, Greece

• Athanasios Pitenis, MD · Private Office, Grevena, Greece

• Eugeneia Karyanou, MD · Private Office, Kaisariani, Athens, Greece

• Georgia Kotantoula, MD · Private Office, Gerakas, Attika, Greece

• Evangelos Bourantzis, MD · Private office, Athens, Greece

• Konstantinos Marosis, MD · Sotiria Pulmonary Hospital of Athens

• Harilaos Lambrakis, MD · Sotiria Pulmonary Hospital of Athens

• Anastasios Palamidas, MD · Sotiria Pulmonary Hospital of Athens

• Dimitrios Zois, MD · General Hospital of Karditsa, Greece

• Maria Varouha, MD · Private office, Rethymno, Crete, Greece

• Karmen Stahouli, MD · Hatzikosta Hospital of Ioannina, Greece

• Peter Oikonomides, MD · General Hospital of Filiata, Thesprotia, Greece

• George Balasoulis, MD · Private office, Thessaloniki, Greece

• Konstantinos Porpodis, MD · Private office, Thessaloniki, Greece

• Despina Melemeni, MD · Sismanogleio Hospital of Athens, Greece

• Andreas Stratis, MD · Private office, Greece

• Efrosini Manali, MD · Attikon University Hospital of Athens, Greece

• Theodora Tsiounta, MD · Theageneio oncology hospital of Thessaloniki, Greece

• Anna Gavriilidou, MD · Papageorgiou hospital of Thessaloniki, Greece

• Athanasia Pataka, MD · Papanikolaou General hospital of Thessaloniki, Greece

• Chrysavgi Terovitou, MD · General hospital of Kavala, Greece

• Elisavet Christina Filippidou, MD · General hospital of Kavala, Greece

• Paschalis Kakavelas, MD · Private office, Piraeus, Greece

• Nikolaos Manolakoglou, MD · Private office, Kalamaria, Thessaloniki, Greece

• Evangelia Tsikrika, MD · General hospital of Veroia, Greece

• Athanasios Papandreou, MD · Private office, Orestiada, Greece

• Vasilios Adamidis, MD · Private office, Kozani, Greece

• Paraskevi Tsafaridou, MD · Private office, Thessaloniki, Greece

• Maria Katertzi, MD · Private office, Moudania, Thessaloniki, Greece

• Pashalia Tsiaga, MD · Private office, Serres, Greece

• Christos Babalis, MD · Private office, Serres, Greece

• Konstantinos Albantakis, MD · Private office, Larisa, Greece

• Martha Andritsou, MD · Sotiria Pulmonology Hospital of Athens

Eligibility

Min Age

18 Years

Max Age

90 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-02-28

Primary Completion

2013-12-31

Completion

2013-12-31

Countries

• Greece

Study Locations