MedTrace Logo

Randomized-controlled Trial (RCT) on CPAP-withdrawal and Microvascular Function in OSA

NCT01797653 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2013-12-23

No results posted yet for this study

Summary

Randomized controlled trial (therapeutic vs. placebo CPAP) including 46 patients with obstructive sleep apnea (OSA) to define the physiological effects of continuous positive airway pressure (CPAP) therapy withdrawal on myocardial perfusion and dermal and renal microvascular function during a 2 week period.

Conditions

  • Obstructive Sleep Apnoea

Interventions

OTHER

CPAP therapy withdrawal

CPAP (continuous positive airway pressure) with subtherapeutic pressure during two weeks

PROCEDURE

Continue CPAP treatment

Continue treatment with therapeutic continuous positive airway pressure device

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Malcolm Kohler, Prof MD · University Hospital Zurich, Division of Pneumology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-02-28
Primary Completion
2013-12-31
Completion
2013-12-31

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01797653 on ClinicalTrials.gov