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RFA (Radiofrequency Ablation) Versus EA (Ethanol Ablation) for Predominantly Cystic Thyroid Nodules

NCT01778400 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2013-11-11

No results posted yet for this study

Summary

Ultrasound-guided ethanol ablation is an effective treatment modality for patients with cystic thyroid nodules (cystic portion \> 90%); however it is less effective in predominantly cystic thyroid nodules (90% \> cystic portions \> 50%). The volume reduction after EA has been reported 64% - 69.8% for predominantly cystic thyroid nodules. EA is insufficient for 26% (27/103) of patients with predominantly cystic thyroid nodules. Radiofrequency ablation to patients with incompletely resolved clinical problems after EA and the mean volume reduction ratio was 92% at 6-month follow-up. It is well known that RF ablation is effective in both predominantly cystic and solid thyroid nodules. Although RF ablation has effectively treated the patients who were unsatisfactory after EA, to the best of our knowledge, no study to date has compared these two ablation techniques. Therefore investigators performed a prospective randomized study to compare single-session RF ablation and EA for treating predominantly cystic thyroid nodules.

Conditions

  • Thyroid Nodule

Interventions

PROCEDURE

radiofrequency ablation

radiofrequency ablation for the treatment as a new therapy as compared with ethanol ablation as a conventional therapy

PROCEDURE

Ethanol ablation

ethanol ablation as a conventional/control therapy to be compared with a new experimental therapy--radiofrequency ablation

Sponsors & Collaborators

  • Asan Medical Center

    lead OTHER

Principal Investigators

  • Jung Hwan Baek, MD · Asan Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-02-28
Primary Completion
2013-05-31
Completion
2014-01-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01778400 on ClinicalTrials.gov