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Pharmacokinetic Interactions of Valsartan and Hydrochlorothiazide

NCT01767259 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2013-01-15

No results posted yet for this study

Summary

This study was conducted to compare the rate and extent of absorption of valsartan and hydrochlorothiazide following oral administration as a fixed dose combination tablet and concomitant administration of the individual drugs under fasting conditions in healthy Egyptian subjects. The study was extended to investigate any potential reaction between VAL and HCT.

Conditions

  • Healthy Normotensive Participants

Interventions

DRUG

Valsartan/Hydrochlorothiazide

Co-administration or fixed dose combination

DRUG

Valsartan

Valsartan alone

DRUG

Hydrochlorothiazide

Hydrochlorothiazide alone

Sponsors & Collaborators

  • Damanhour University

    lead OTHER

Principal Investigators

  • Sally Helmy, PhD, CPHQ · Pharmaceutics Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2012-12-31
Completion
2012-12-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01767259 on ClinicalTrials.gov