Exosomal MicroRNA Expression in Children With Autism Spectrum Disorder
NCT01749670 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45
Last updated 2014-11-26
Summary
There is accumulating evidence that genetic expression plays a role in autism spectrum disorder, but the regulation of such genes is poorly understood. Small RNA particles, called microRNA (miRNA), have the ability to alter gene expression. These particles can be packaged and released from brain cells into the blood. Changes in miRNA may contribute to the patterns observed in autism spectrum disorder.
The purpose of this study is to identify small RNA particles that regulate gene expression in autism spectrum disorder. The goal is to identify miRNA expression patterns which may improve our understanding and diagnosis of autism spectrum disorder.
Conditions
Sponsors & Collaborators
-
State University of New York - Upstate Medical University
lead OTHER
Principal Investigators
-
Steven Hicks, MD, PhD · SUNY Upstate Medical University, Department of Pediatrics
Eligibility
- Min Age
- 4 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-01-31
- Primary Completion
- 2014-09-30
- Completion
- 2014-09-30
Countries
- United States
Study Locations
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