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Study to See if Platelet Transfusion Stop or Lessen the Effect of the Drug on Platelets

NCT01744288 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 258

Last updated 2014-04-24

No results posted yet for this study

Summary

Study to see if platelet transfusion stop or lessen the effect of the drug on platelets

Conditions

  • Inhibition on Platelet Aggregation

Interventions

DRUG

Ticagrelor

Oral single loading dose 180ng

DRUG

Clopidogrel

Oral single loading dose 600mg

DRUG

ASA

81mg once daily from day -2 up to platelet transfusion

Sponsors & Collaborators

Principal Investigators

  • Glenn Carlson, MD · AstraZeneca Wilmington US

  • Phil Leese, MD · Overland Park US, Quintiles, Inc

  • Judi Hsia, MD · Wilmington, US AstraZeneca

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2014-04-30
Completion
2014-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01744288 on ClinicalTrials.gov