The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'

NCT01737047 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1377

Last updated 2025-09-18

Study results available
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Summary

The purpose of this study is to identify medical conditions that may cause particular problems to individuals receiving care for HIV infection over the age of 50. In addition, as the effects and potentially the side effects, of HIV medication may change with age, this study will also investigate the association between age and differing effects of antiretroviral therapies such as treatment outcomes, side effects and the levels of drugs in blood.

Results from this study may inform future HIV treatment guidelines on how individuals with HIV infection are monitored. The results may also assist in the design of future studies for the treatment of diseases associated with ageing.

Conditions

  • HIV Positive
  • Ageing

Sponsors & Collaborators

Principal Investigators

  • Caroline Sabine, PhD · University College, London

  • Alan Winston, MD · Imperial College London

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-04-01
Primary Completion
2018-01-31
Completion
2023-03-13

Countries

  • Ireland
  • United Kingdom

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01737047 on ClinicalTrials.gov