Survival of Implant-Supported All-Ceramic Prostheses

Summary

The purpose of this research study is to identify reasons that cause an all-ceramic bridge to fracture which include the thickness of the bridge material, the type of bridge material and the bite force of the person. This all-ceramic bridge will be compared to a metal-ceramic bridge. The investigators are conducting this study so we can make bridges which can withstand forces in the mouth which tend to break them.

The overall objective of this research is to analyze how properties of ceramic materials and different forces in the mouth interact with each other to affect the longevity of these bridges. These include fracture toughness, elastic modulus of ceramic layers and supporting substrate, core thickness, connector height, wear, loading orientation, and maximum clenching force.

Conditions

• Partial Edentulism
• Disorder of Prostheses and Implants
• Dental Prosthesis Failure

Interventions

DEVICE

Ceramic-Ceramic

Zirconia computer aided design and computer milled cores with press on veneers with different thicknesses, gingival embrasure diameters and connector heights. Fifty percent of the recruited subjects will be given a ceramic-ceramic bridge at baseline.

DEVICE

Metal-Ceramic

Metal Ceramic prosthesis with press on veneer with different thicknesses, different diameters of curvature of gingival embrasure and connector heights. Fifty percent of the recruited subjects will receive the metal-ceramic bridges at baseline.

Sponsors & Collaborators

• National Institute of Dental and Craniofacial Research (NIDCR)

  collaborator NIH

• Ivoclar Vivadent AG

  collaborator INDUSTRY

• Dentsply Sirona Inc.

  collaborator INDUSTRY

• University of Florida

  lead OTHER

Principal Investigators

• Josephine F Esquivel-Upshaw, DMD,MS,MS-CI · University of Florida

• Kenneth J Anusavice, PhD, DMD · University of Florida

• Arthur E Clark, PhD, DMD · University of Florida

Eligibility

Min Age

21 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2008-12-31

Primary Completion

2026-12-31

Completion

2028-12-31

FDA Device

Yes

Countries

• United States

Study Locations