Effect of Omeprazole on Metformin
NCT01711320 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2013-03-19
Summary
In this study, investigators hypothesized that the plasma concentration of metformin and its glucose-lowering action would be affected by omeprazole, probably by altering the expression or function of OCTs in the liver, its primary target organ, as well as in the kidney.
Conditions
- Healthy
Interventions
- DRUG
- DRUG
-
Omeprazole
Sponsors & Collaborators
-
Xijing Hospital
lead OTHER
Principal Investigators
-
AiDong Wen, Pro · Department of pharmacy, Xijing Hospital, Fourth Military Medical University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-09-30
- Primary Completion
- 2012-12-31
- Completion
- 2012-12-31
Countries
- China
Study Locations
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