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Isolated Erythrocyte Membrane Susceptibility to Photo-oxidative Stress in Alzheimer's Disease

NCT01707719 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2020-01-23

No results posted yet for this study

Summary

High lipid peroxidation and altered antioxidant defenses have been frequently reported in Alzheimer's disease patients.

The purpose of this study is to investigate susceptibility to photo-oxidation of isolated erythrocyte membranes, in patients affected by Alzheimer's disease and age- and sex-matched, non demented subjects.

Conditions

  • Alzheimer Disease
  • Oxidative Stress
  • Adrenocortical Hyperfunction

Sponsors & Collaborators

  • Raffaele Antonelli Incalzi

    lead OTHER

Principal Investigators

  • Francesco Maria Serino, M.D. PhD · Doctors in Italy

  • Chiara Fanali, PhD · University Campus Bio-Medico

  • Laura Dugo, PhD · University Campus Bio-Medico

  • Simone Grasso, PhD · University Campus Bio-Medico

  • Ettore Bergamini, M.D. · University of Pisa

  • Francesca Ursini, M.D. · University Campus Bio-Medico

  • Fabrizio Vernieri, M.D. · University Campus Bio-Medico

  • Marina Dachà, BS.Pharm · University Campus Bio-Medico

  • Silvia Bernardini, M.D. · University Campus Bio-Medico

  • Valentina Pasqualetti, PhD · University Campus Bio-Medico

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-06-30
Primary Completion
2018-11-30
Completion
2018-11-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01707719 on ClinicalTrials.gov