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Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial)

NCT01696981 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 154900

Last updated 2026-04-30

Study results available
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Summary

This clinical trial studies whether screening methods used to diagnose cancer of the prostate, lung, colon, rectum, or ovaries can reduce deaths from these cancers. Screening tests may help doctors find cancer cells early and plan better treatment for colorectal cancer.

Conditions

  • Colon Carcinoma
  • Rectal Carcinoma

Interventions

OTHER

Screening Questionnaire Administration

Undergo questionnaire assessments

PROCEDURE

Sigmoidoscopy

Undergo a flexible sigmoidoscopy

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    lead NIH

Principal Investigators

  • Christine D Berg · National Cancer Institute (NCI)

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Max Age
74 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1993-11-16
Primary Completion
2012-05-21
Completion
2027-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01696981 on ClinicalTrials.gov