Trial Outcomes & Findings for Advanced Image Guidance Utilized in Liver Surgery (NCT NCT01666145)

NCT ID: NCT01666145

Last Updated: 2022-04-22

Results Overview

Once the ablation antenna has been placed into the target lesion, the success or failure of the attempt will be confirmed with conventional ultrasound alone, in two planes. If the placement is deemed successful, the surgeon will commence the ablation of the tumor. If the placement is deemed insufficient, the probe will be removed and another placement will be attempted using conventional guidance.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

14 participants

Primary outcome timeframe

Participants will be followed for the duration of hospital stay, an expected average of 2 to 3 days.

Results posted on

2022-04-22

Participant Flow

Participant milestones

Participant milestones
Measure
Intraoperative Imaging
Laparoscopic microwave ablation surgery utilizing the Advanced Image Guidance system for needle placement. Advanced Image Guidance: Patients with hepatocellular carcinoma will be treated through laparoscopic microwave ablation surgery, in which the surgeon will utilize a new guidance system for needle placement.
Overall Study
STARTED
14
Overall Study
COMPLETED
14
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Advanced Image Guidance Utilized in Liver Surgery

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intraoperative Imaging
n=14 Participants
Laparoscopic microwave ablation surgery utilizing the Advanced Image Guidance system for needle placement. Advanced Image Guidance: Patients with hepatocellular carcinoma will be treated through laparoscopic microwave ablation surgery, in which the surgeon will utilize a new guidance system for needle placement.
Age, Continuous
63 years
n=39 Participants
Sex: Female, Male
Female
5 Participants
n=39 Participants
Sex: Female, Male
Male
9 Participants
n=39 Participants
Region of Enrollment
United States
14 participants
n=39 Participants

PRIMARY outcome

Timeframe: Participants will be followed for the duration of hospital stay, an expected average of 2 to 3 days.

Once the ablation antenna has been placed into the target lesion, the success or failure of the attempt will be confirmed with conventional ultrasound alone, in two planes. If the placement is deemed successful, the surgeon will commence the ablation of the tumor. If the placement is deemed insufficient, the probe will be removed and another placement will be attempted using conventional guidance.

Outcome measures

Outcome measures
Measure
Intraoperative Imaging
n=14 Participants
Laparoscopic microwave ablation surgery utilizing the Advanced Image Guidance system for needle placement. Advanced Image Guidance: Patients with hepatocellular carcinoma will be treated through laparoscopic microwave ablation surgery, in which the surgeon will utilize a new guidance system for needle placement.
Successful Insertion of Ablation Antenna Into Target Lesion
100 percentage of participants

SECONDARY outcome

Timeframe: Participants will be followed for the duration of hospital stay, an expected average of 2 to 3 days.

A subjective grading scale from which the surgeon will provide the relative ease of lesion targeting using Advanced Image Guidance (AIM) and the guidance system; the scale will be numbered 1-5 with one being significantly difficult and five being significantly easy. The percentage of participants with a score of 5 is reported below.

Outcome measures

Outcome measures
Measure
Intraoperative Imaging
n=14 Participants
Laparoscopic microwave ablation surgery utilizing the Advanced Image Guidance system for needle placement. Advanced Image Guidance: Patients with hepatocellular carcinoma will be treated through laparoscopic microwave ablation surgery, in which the surgeon will utilize a new guidance system for needle placement.
Percentage of Participants With Significant Ease of Lesion Targeting Using Advanced Image Guidance (AIM)
100 percentage of participants

Adverse Events

Intraoperative Imaging

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Principal Investigator

Carolinas Healthcare System

Phone: 704-446-2772

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place