Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis
NCT01659619 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 114
Last updated 2013-02-21
Summary
Erythromycin has a prokinetic effect through Motilin receptor. It evokes migrating motor complex with longer and stronger contraction.
In patients with upper gastrointestinal bleeding, It has been shown that erythromycin could clear the stomach of blood, so visual examination could be improved.
Frequent food stasis is encounted when we examine patients with subtotal gastrectomy. It is postulated that erythromycin reduce food stasis and help to improve endoscopy in these cases.
Conditions
- Subtotal Gastrectomy
- Stomach Cancer
Interventions
- DRUG
-
Erythromycin
125mg in normal saline single use infusion for 5 min.
Sponsors & Collaborators
-
The Catholic University of Korea
lead OTHER
Principal Investigators
-
Myung-Gyu Choi, M.D. · Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-04-30
- Primary Completion
- 2012-10-31
- Completion
- 2012-10-31
Countries
- South Korea
Study Locations
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