Impact of Hand Hygiene Activities on the Prevention of Intestinal Parasitic Infections and Anaemia Among School Children

Summary

Impact exerted by intestinal parasitic infections is much higher in developing countries. School-aged children are at higher risk from the burden of disease, because they specially have many parasitic infections. The poor health results in deficits in physical and cognitive development and educational achievements. Nowadays, there is huge commitment among the global community to control intestinal parasitic infections and to improve nutritional status of young children in developing countries.

Large-scale anthelminthic drug administration through vertical control programmes is still required for the foreseeable future and is, therefore, recommended by the World Health Organization (WHO). However, due to the inevitability of re-infection in endemic areas, children need to be treated regularly, and once morbidity control is consolidated, the strategy must shift to transmission control emphasising access to clean water and adequate sanitation. To lower dependency on 'drug only' approach and to enhance sustainability, from the onset of control activities, complementary measures should be implemented, that depend on available resources.

Therefore, the investigators are proposing to undertake a randomised controlled trial to assess the impact of simple and easy-to-do hand hygiene intervention packages (hand washing with soap and hand finger nail clipping) on intestinal parasitic infection prevalence, intensity and re-infection rates and on haemoglobin concentration and anaemia prevalence rates among 6-15 years old schoolchildren. Our results will provide solid evidence on if and how hand hygiene practice affects infection prevalence and re-infection rates, as well as, anaemia prevalence among the highly vulnerable age group.

Conditions

• Intestinal Parasitic Infections
• Anaemia

Interventions

BEHAVIORAL

Hand washing with soap and hand finger nail clipping

Assess the impact of hand washing with soap and nail clipping on child health

Sponsors & Collaborators

• University of Alcala

  collaborator OTHER

• Maastricht University

  collaborator OTHER

• Mekelle University

  lead OTHER

Principal Investigators

• Mahmud Ab Mahmud, PhD fellow · College of Health Scieneces, Mekelle University

• Roman B Velasco, MD, PhD · Alcala University, Madrid, Spain

• Mark Spigt, MSC, PhD · Maastricht University, The Netherlands

• Afework M Bezabeh, MSC, PhD · College of Health Sciences, Mekelle University

• Geert J Dinant, Professor · Maastricht University, The Netherlands

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

FACTORIAL

Eligibility

Min Age

6 Years

Max Age

15 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2012-07-31

Primary Completion

2013-02-28

Completion

2013-02-28

Countries

• Ethiopia

Study Locations