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Assessment of Visual Field-related Endpoints in Patients With Non-arteritic Ischemic Optic Neuropathy

NCT01614158 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 16

Last updated 2014-05-28

No results posted yet for this study

Summary

This present research project intends to collect five quantitative test series:

* perimetric examination using static stimuli, assessing the entire (80 degree) visual field with a fast thresholding algorithm (GATE) \[Schiefer 2008\] to know the extent/ magnitude of the visual field defect and its variability within the cohort and over time
* D-BCVA, using FrACT \[Bach 2007\] and EDTRS chart \[Ferris 1982\]
* RAPD (using swinging flashlight test).
* IOP (using applanation tonometer)
* RNFT and RNFV using Spectralis OCT (star scan, ring scan 2,8 mm, and volume scan) Optic disk morphology will be documented by fundus photography. This assessment of the above-mentioned data is needed in order to allow for estimation of the spontaneous course / fluctuation of the (quantified) functional and morphometric parameters of the N-AION patients during the follow-up period. This is essential for the estimation of the sample size of the subsequently intended SINN study, that is intended to compare different therapeutic strategies in N-AION patients.

Conditions

  • Non-arteritic Ischemic Optic Neuropathy

Interventions

DEVICE

perimetry

perimetric examination using static stimuli, assessing the entire (80 degree) visual field with a fast thresholding algorithm (GATE) \[Schiefer 2008\] to know the extent/ magnitude of the visual field defect and its variability within the cohort and over time

OTHER

D-BCVA

D-BCVA using EDTRS chart

OTHER

RAPD

RAPD using swinging flashlight test

DEVICE

IOP

IOP using applanation tonometer

DEVICE

Spectralis OCT

RNFT and RNFV using Spectralis OCT (star scan, ring scan 2,8 mm and volume scan)

OTHER

Fundus photography

Optic disk morphology will be documented by fundus photography

Sponsors & Collaborators

  • University Hospital Freiburg

    collaborator OTHER

  • University Hospital Tuebingen

    lead OTHER

Principal Investigators

  • Ulrich Schiefer, Prof. · Centre for Ophthalmology Institute for Ophthalmic Research University of Tübingen

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-04-30
Primary Completion
2011-02-28
Completion
2011-02-28

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01614158 on ClinicalTrials.gov