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Radical Fimbriectomy for Young BRCA Mutation Carriers

NCT01608074 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 123

Last updated 2026-03-18

No results posted yet for this study

Summary

Some BRCA-mutated women are reluctant to undergo laparoscopic bilateral salpingo-oophorectomy. The goal of the bilateral laparoscopic radical fimbriectomy the investigators suggest, is to suppress the tubal source of possible dysplastic cells from which can stem this high grade tumor, while preserving a natural ovarian hormonal secretion.

Conditions

  • BRCA1 Mutation
  • BRCA2 Mutation
  • Hereditary Breast and Ovarian Cancer

Interventions

PROCEDURE

Radical fimbriectomy

Laparoscopic bilateral radical fimbriectomy : Complete resection of the tubes, from the uterine tube (up against the uterus) to the fimbriae, with resection of the part of the ovary adjacent to the ovarian fimbriae (adhering to the ovary)

OTHER

Histopathology SEE-FIM

Anatomopathological study of surgical specimens

Sponsors & Collaborators

  • CTD-CNO

    collaborator UNKNOWN

  • Laboratoire PRISM

    collaborator UNKNOWN

  • Centre Oscar Lambret

    lead OTHER

Principal Investigators

  • Carlos MARTINEZ-GOMEZ, MD · Centre Oscar Lambret

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-09
Primary Completion
2033-08-31
Completion
2033-08-31

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01608074 on ClinicalTrials.gov