Trial Outcomes & Findings for Transcutaneous Electrical Nerve Stimulation for Pain Relief During the Active Phase of Labor (NCT NCT01600495)

NCT ID: NCT01600495

Last Updated: 2015-10-05

Results Overview

To evaluate the Transcutaneous Electrical Nerve Stimulation as a resource for pain relief during the active phase of labor will be used the Visual Analogue Scale. Visual analogue scale (VAS): this scale, represented by a rule, the patient estimated pain on a scale of 100 mm (at one end labeled "no pain" associated with a score of 0 mm and at the other end "worst pain imagined" with a score 100 mm)

Recruitment status

COMPLETED

Study phase

PHASE4

Target enrollment

46 participants

Primary outcome timeframe

30 minutes

Results posted on

2015-10-05

Participant Flow

A randomized, controlled clinical noninferiority with an evaluator blind, comparative analysis of a study group and a control group, this estdo includes 46 patients, was developed in the Reference Center for Women's Health in Ribeirão Preto, São Paulo state Brazil, during the period September 2011 to February 2012 .

283 women in labor were eligible, women were excluded because they did not participate 237 the inclusion criteria (first pregnancy, the position of a single fetus head, above 37 weeks, 4-5 cm of cervical dilatation, spontaneous onset of labor, not use of medications during the study period, intact membranes, and not associated with risk factors).

Participant milestones

Participant milestones
Measure
Experimental TENS
TENS Intervention Group(GIE) used for 30 minutes, during uterine contractions between 4-5 cm
Control Group
Formed by mothers who will not use EAC to receive the routine procedures of motherhood, but will be monitored and evaluated at the same time in the intervention group.
Overall Study
STARTED
23
23
Overall Study
COMPLETED
23
23
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Transcutaneous Electrical Nerve Stimulation for Pain Relief During the Active Phase of Labor

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Experimental TENS
n=23 Participants
TENS Intervention Group(GIE) used for 30 minutes, during uterine contractions between 4-5 cm
Control Group
n=23 Participants
Formed by mothers who will not use EAC to receive the routine procedures of motherhood, but will be monitored and evaluated at the same time in the intervention group.
Total
n=46 Participants
Total of all reporting groups
Age, Categorical
<=18 years
12 Participants
n=99 Participants
9 Participants
n=107 Participants
21 Participants
n=206 Participants
Age, Categorical
Between 18 and 65 years
11 Participants
n=99 Participants
14 Participants
n=107 Participants
25 Participants
n=206 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Age, Continuous
19.8 years
STANDARD_DEVIATION 3.9 • n=99 Participants
19.8 years
STANDARD_DEVIATION 3.7 • n=107 Participants
19.8 years
STANDARD_DEVIATION 3.8 • n=206 Participants
Sex: Female, Male
Female
23 Participants
n=99 Participants
23 Participants
n=107 Participants
46 Participants
n=206 Participants
Sex: Female, Male
Male
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Region of Enrollment
Brazil
23 participants
n=99 Participants
23 participants
n=107 Participants
46 participants
n=206 Participants

PRIMARY outcome

Timeframe: 30 minutes

Population: We evaluated 46 patients, divided into 23 ENT group and 23 in the control group.

To evaluate the Transcutaneous Electrical Nerve Stimulation as a resource for pain relief during the active phase of labor will be used the Visual Analogue Scale. Visual analogue scale (VAS): this scale, represented by a rule, the patient estimated pain on a scale of 100 mm (at one end labeled "no pain" associated with a score of 0 mm and at the other end "worst pain imagined" with a score 100 mm)

Outcome measures

Outcome measures
Measure
Experimental TENS
n=23 Participants
TENS Intervention Group(GIE) used for 30 minutes, during uterine contractions between 4-5 cm
Control Group
n=23 Participants
Formed by mothers who will not use EAC to receive the routine procedures of motherhood, but will be monitored and evaluated at the same time in the intervention group.
Classification of Pain During Labor by Visual Analogue Scale
57.0 mm
Standard Deviation 23.4
72.1 mm
Standard Deviation 15.4

SECONDARY outcome

Timeframe: 10 hours

Population: Analyzing the date of application of pharmacological analgesia.

Consider whether the TENS therapy during the active phase of labor could defer request for analgesia use for pain relief for pregnant women. The cervical dilation indicates the value in centimeters (0-10) of cervical dilation. Assessed on admission and during labor by doctors (according to the routine of the institution), as recorded in medical records.

Outcome measures

Outcome measures
Measure
Experimental TENS
n=23 Participants
TENS Intervention Group(GIE) used for 30 minutes, during uterine contractions between 4-5 cm
Control Group
n=23 Participants
Formed by mothers who will not use EAC to receive the routine procedures of motherhood, but will be monitored and evaluated at the same time in the intervention group.
Evaluation of TENS During the Active Phase of Labor Over the Use of Analgesia
7.0 cm
Standard Deviation 1.72
6.41 cm
Standard Deviation 1.18

SECONDARY outcome

Timeframe: 10 hours

Population: Analyzing the duration of labor

The length of time of labor, specified number of minutes since the opening of the partograph (early labor) until the birth of the child.

Outcome measures

Outcome measures
Measure
Experimental TENS
n=23 Participants
TENS Intervention Group(GIE) used for 30 minutes, during uterine contractions between 4-5 cm
Control Group
n=23 Participants
Formed by mothers who will not use EAC to receive the routine procedures of motherhood, but will be monitored and evaluated at the same time in the intervention group.
Duration From Start of Labor Until Birth
393 min
Standard Deviation 139.4
322 min
Standard Deviation 75.6

SECONDARY outcome

Timeframe: 10 hours

Population: All patients were invited to answer the questionnaire.

Simple questionnaire (Questionnaire satisfaction of parturients with comparision with experience in this study) developed for this study with 3 items (yes, no and do not want to answer) to assess satisfaction of mothers in the intervention group and the control group regarding the presence of a professional during the period of study and experience in this work.

Outcome measures

Outcome measures
Measure
Experimental TENS
n=23 Participants
TENS Intervention Group(GIE) used for 30 minutes, during uterine contractions between 4-5 cm
Control Group
n=23 Participants
Formed by mothers who will not use EAC to receive the routine procedures of motherhood, but will be monitored and evaluated at the same time in the intervention group.
Number of Participants Who Were Satisfied With the Presence of a Professional/Physiotherapist During Labor.
17 participants
7 participants

Adverse Events

Experimental TENS

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Prof. Alessandra Cristina Marcolin

University of São Paulo.

Phone: Tel.: (16) 36022587

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place