Trial Outcomes & Findings for Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft (NCT NCT01588444)

NCT ID: NCT01588444

Last Updated: 2015-10-22

Results Overview

Histologic percentage of vital bone formation in bone cores

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

40 participants

Primary outcome timeframe

18-20 weeks after grafting

Results posted on

2015-10-22

Participant Flow

Participant milestones

Participant milestones
Measure
Cancellous FDBA (LifeNet)
grafting with cancellous mineralized freeze-dried bone allograft (LifeNet Health) Cancellous FDBA: CANCELLOUS FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health)
Cortical FDBA (LifeNet)
CORTICAL FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health) cortical FDBA: cortical mineralized freeze-dried bone allograft
Overall Study
STARTED
20
20
Overall Study
COMPLETED
20
20
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Cancellous FDBA (LifeNet)
n=20 Participants
grafting with cancellous mineralized freeze-dried bone allograft (LifeNet Health) Cancellous FDBA: CANCELLOUS FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health)
Cortical FDBA (LifeNet)
n=20 Participants
CORTICAL FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health) cortical FDBA: cortical mineralized freeze-dried bone allograft
Total
n=40 Participants
Total of all reporting groups
Age, Continuous
53.4 years
n=99 Participants
55.6 years
n=107 Participants
54 years
n=206 Participants
Age, Categorical
<=18 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Age, Categorical
Between 18 and 65 years
17 Participants
n=99 Participants
16 Participants
n=107 Participants
33 Participants
n=206 Participants
Age, Categorical
>=65 years
3 Participants
n=99 Participants
4 Participants
n=107 Participants
7 Participants
n=206 Participants
Sex: Female, Male
Female
9 Participants
n=99 Participants
10 Participants
n=107 Participants
19 Participants
n=206 Participants
Sex: Female, Male
Male
11 Participants
n=99 Participants
10 Participants
n=107 Participants
21 Participants
n=206 Participants
Region of Enrollment
United States
20 participants
n=99 Participants
20 participants
n=107 Participants
40 participants
n=206 Participants

PRIMARY outcome

Timeframe: 18-20 weeks after grafting

Histologic percentage of vital bone formation in bone cores

Outcome measures

Outcome measures
Measure
Cancellous FDBA (LifeNet)
n=20 Participants
grafting with cancellous mineralized freeze-dried bone allograft (LifeNet Health) Cancellous FDBA: CANCELLOUS FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health)
Cortical FDBA (LifeNet)
n=20 Participants
CORTICAL FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health) cortical FDBA: cortical mineralized freeze-dried bone allograft
Histologic Percentage of Vital Bone Formation
12.98 percentage of vital bone
Interval 10.06 to 31.04
16.08 percentage of vital bone
Interval 12.12 to 30.25

Adverse Events

Cancellous FDBA (LifeNet)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Cortical FDBA (LifeNet)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Brian Mealey

UT Health Sci Ctr San Antonio

Phone: 210-567-3567

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place