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Normalizing CO2 in Chronic Hyperventilation by a Novel Breathing Mask: A Pilot Study

NCT01575665 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2016-05-19

No results posted yet for this study

Summary

Background: Chronic Idiopathic Hyperventilation (CIH) is a form of dysfunctional breathing which has proven hard to treat effectively. The investigators hypothesised that by periodically inducing normocapnia over several weeks, it would be possible to raise the normal resting level/set point of CO2 and achieve a reduction of symptoms.

Methods: Six CIH patients were treated two hours a day for four weeks with a novel breathing mask. The mask was used to induce normocapnia in these chronically hypocapnic patients.

Capillary blood gases (PcCO2, pH, Standard Base Excess (SBE) etc.) were measured at baseline and once each week at least three hours after mask use, as well as spirometric values, breath holding tolerance and hyperventilation symptoms as per the Nijmegen Questionnaire (NQ),.

Conditions

  • Hyperventilation
  • Chronic Idiopathic Hyperventilation
  • Dysfunctional Breathing
  • Respiratory Alkalosis

Interventions

DEVICE

Partial Rebreathing Mask

Inducing normal CO2 for two hours a day for four weeks

Sponsors & Collaborators

  • Rehaler

    collaborator INDUSTRY

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Ronald Dahl · Aarhus University Hospital

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2011-06-30
Completion
2011-06-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01575665 on ClinicalTrials.gov