aHUS Observational Long Term Follow-Up
NCT01522170 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 94
Last updated 2017-02-24
Summary
There is growing but limited information on the long term clinical status of aHUS patients who have previously received or are continuing to receive treatment with eculizumab. This study is designed to collect clinical data that will provide insight into the long-term outcomes of patients with aHUS.
Conditions
- Atypical Hemolytic Uremic Syndrome
Sponsors & Collaborators
-
Alexion Pharmaceuticals, Inc.
lead INDUSTRY
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-03-31
- Primary Completion
- 2017-01-31
- Completion
- 2017-01-31
Countries
- United States
- Australia
- Austria
- Belgium
- Canada
- France
- Germany
- Italy
- Netherlands
- Sweden
- Switzerland
- United Kingdom
Study Locations
More Related Trials
-
Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)
NCT00838513 ·Status: COMPLETED ·Phase: PHASE2
-
Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS
NCT00844844 ·Status: COMPLETED ·Phase: PHASE2
-
Eculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in China
NCT05876351 ·Status: COMPLETED ·Phase: PHASE3
-
Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT02949128 ·Status: COMPLETED ·Phase: PHASE3
-
An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome
NCT01194973 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Ravulizumab in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT03131219 ·Status: COMPLETED ·Phase: PHASE3
-
Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS
NCT07308574 ·Status: RECRUITING ·Phase: PHASE4
-
The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT01757431 ·Status: COMPLETED ·Phase: PHASE2
-
Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS
NCT00844428 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT04861259 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea
NCT05405777 ·Status: COMPLETED
-
Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy
NCT05684159 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy
NCT05805202 ·Status: RECRUITING ·Phase: NA
-
Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab
NCT00122304 ·Status: COMPLETED ·Phase: PHASE3
-
Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome
NCT05726916 ·Status: RECRUITING ·Phase: PHASE3
-
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT04958265 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Complement Inhibition in aHUS Dialysis Patients
NCT02464891 ·Status: TERMINATED ·Phase: PHASE2
-
Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS
NCT05795140 ·Status: RECRUITING ·Phase: PHASE3
-
Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)
NCT04859608 ·Status: COMPLETED ·Phase: PHASE3
-
Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients
NCT00122330 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome
NCT03303313 ·Status: WITHDRAWN ·Phase: PHASE2
-
ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab
NCT03056040 ·Status: COMPLETED ·Phase: PHASE3
-
E07-001: Safety and Efficacy Extension Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients
NCT01194804 ·Status: COMPLETED ·Phase: PHASE2
-
Observational Study of Elizaria® in aHUS Patients
NCT04749810 ·Status: COMPLETED
-
Rescue of Nephrons With ALE.F02 (RENAL-F02)
NCT06047171 ·Status: RECRUITING ·Phase: PHASE2