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Comparison of Temazepam and Acetazolamide to Treat Difficulty Sleeping at High Altitude

NCT01519544 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2015-04-23

No results posted yet for this study

Summary

More than 70% of visitors to high altitude suffer poor sleep. The present study seeks to answer the question: Which medication is associated with better sleep at high altitude: temazepam or acetazolamide? The investigators hypothesis is that one medication will be associated with higher subjective sleep scores than the other. The study will compare the sleep quality of 100 subjects as they take either temazepam or acetazolamide during a visit to high altitude.

Conditions

  • High-altitude Sleep Disturbance

Interventions

DRUG

Temazepam

Temazepam 7.5mg capsule to be taken by mouth at bedtime for one night only.

DRUG

Acetazolamide

Take Acetazolamide 125mg tablet by mouth at bedtime for one night only.

Sponsors & Collaborators

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Norman S Harris, MD, MFA · Massachusetts General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-03-31
Primary Completion
2012-07-31
Completion
2015-03-31

Countries

  • Nepal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01519544 on ClinicalTrials.gov